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Secretogranin II (SCG2) Antibody – Goat

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423191

MBS423191 is an antibody targeting SCG2. Also known as Goat anti-secretogranin II (aa203-217) Antibody. Reactive in Tested: HumanExpected from sequence similarity: Human, Dog, Pig. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
secretogranin II (SCG2), Antibody
Full Product Name
Goat anti-secretogranin II (aa203-217) Antibody
Product Gene Name
Product Synonym Names
SCG2, secretogranin II, CHGC, EM66, SN, SgII, chromogranin-C, secretogranin-2, secretoneurin
Host
Goat
Species Reactivity
Tested: Human
Expected from sequence similarity: Human, Dog, Pig
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
OMIM
118930
Immunogen
Peptide with sequence C-QELGKLTGPNNQKRE, from the internal region of the protein sequence according to NP_003460.2.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SCG2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SCG2 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 70kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 70.9kDa according to NP_003460.2). Recommended concentration: 0.3-1ug/ml.

Western Blot (WB) of anti-SCG2 antibody

(0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SCG2 Antibody – Cat# MBS423191

Other Notes

Small volumes of anti-SCG2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SCG2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
secretogranin-2
NCBI Official Synonym Full Names
secretogranin II
NCBI Official Symbol
SCG2
NCBI Official Synonym Symbols
SN; CHGC; EM66; SgII
UniProt Protein Name
Secretogranin-2
UniProt Synonym Protein Names
Chromogranin-C; Secretogranin II; SgII
Protein Family
UniProt Gene Name
SCG2
UniProt Synonym Gene Names
CHGC; SgII; SN
UniProt Entry Name
SCG2_HUMAN
NCBI Protein Information
secretogranin-2

NCBI Summary for SCG2

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008]
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UniProt Comments for SCG2

SCG2: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Belongs to the chromogranin/secretogranin protein family.

Protein type: Cytokine; Secreted; Cell cycle regulation; Motility/polarity/chemotaxis; Apoptosis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2q35-q36

Cellular Component: extracellular space

Molecular Function: chemoattractant activity; cytokine activity; protein binding

Biological Process: angiogenesis; endothelial cell migration; eosinophil chemotaxis; induction of positive chemotaxis; inflammatory response; MAPKKK cascade; negative regulation of endothelial cell proliferation; positive chemotaxis; positive regulation of endothelial cell proliferation; protein secretion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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