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APOBEC3D Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423234

MBS423234 is an antibody targeting APOBEC3D. Also known as Goat anti-APOBEC3D Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
APOBEC3D, Polyclonal Antibody
Full Product Name
Goat anti-APOBEC3D Antibody
Product Gene Name
Product Synonym Names
Goat Anti-APOBEC3D (aa61-74) Antibody; APOBEC3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D (putative); ARP6; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; APOBEC3D antibody; apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3D (putative) antibody; ARP6 antibody; apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3D antibody
Immunogen Sequence
ATDSQETRPG RA
Clonality
Polyclonal
Host
Goat
Species Reactivity
Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
APOBEC3D peptide (MBS428131) is used for blocking the activity of APOBEC3D antibody (MBS423234)
Molecular Weight
46,598 Da
OMIM
609900
Immunogen
Peptide with sequence C-ATDSQETRPGRA, from the internal region of the protein sequence according to NP_689639.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-APOBEC3D antibody
Peptide ELISA (EIA)
Application Notes for anti-APOBEC3D antibody
Peptide ELISA: Antibody detection limit dilution 1: 1000.
Western Blot: Preliminary experiments gave an approx 38kDa band in lysates of cell lines A549 and HeLa after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 31.7kDa according to NP_689639.1. The 38kDa band was successfully blocked by incubation with the immunizing peptide.

Other Notes

Small volumes of anti-APOBEC3D antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for APOBEC3D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
NCBI Official Synonym Full Names
apolipoprotein B mRNA editing enzyme catalytic subunit 3D
NCBI Official Symbol
APOBEC3D
NCBI Official Synonym Symbols
A3D; ARP6; APOBEC3E; APOBEC3DE
UniProt Protein Name
DNA dC->dU-editing enzyme APOBEC-3D
UniProt Gene Name
APOBEC3D
UniProt Synonym Gene Names
A3D
UniProt Entry Name
ABC3D_HUMAN
NCBI Protein Information
DNA dC->dU-editing enzyme APOBEC-3D

NCBI Summary for APOBEC3D

This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008]
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UniProt Comments for APOBEC3D

APOBEC3D: Probable DNA cytidine deaminase involved in foreign DNA clearance. May provide cellular innate resistance to a specific panel of genetic invaders including endogenous retroelements and a subset of viruses. Belongs to the cytidine and deoxycytidylate deaminase family.

Protein type: Hydrolase; EC 3.5.4.-

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: cytoplasm

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; zinc ion binding

Biological Process: defense response to virus; innate immune response; negative regulation of retroviral genome replication
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-APOBEC3D antibody

 Organ/Tissue Name  Pubmed Publications
 Thymus Antibodies  >1 publications with APOBEC3D and Thymus
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