Goat Anti-CD3EAP Polyclonal Antibody – Cat# MBS423351

CD3EAP Antibody – Goat Polyclonal

Name: CD3EAP Antibody; Polyclonal; Goat; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS423351
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423351

MBS423351 is an antibody targeting CD3EAP. Also known as Goat anti-CD3EAP Antibody. Reactive in Expected from sequence similarity: Human. Host: Goat. More details

$305 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD3EAP, Polyclonal Antibody

Full Product Name

Goat anti-CD3EAP Antibody

Product Gene Name

anti-CD3EAP antibody

Product Synonym Names

CD3EAP; CD3e molecule, epsilon associated protein; ASE-1; ASE1; CAST; PAF49; A34.5; CD3 epsilon associated protein; CD3-epsilon-associated protein; CD3E-associated protein; CD3e antigen, epsilon polypeptide associated protein; DNA-directed RNA polymerase; CD3EAP antibody; CD3e molecule; epsilon associated protein antibody; ASE-1 antibody; ASE1 antibody; CAST antibody; PAF49 antibody; A34.5 antibody; CD3 epsilon associated protein antibody; CD3-epsilon-associated protein antibody; CD3E-associated protein antibody; CD3e antigen; epsilon polypeptide associated protein antibody; DNA-directed RNA polymerase antibody

Immunogen Sequence

PEDKTVKQEQ INTEP

Clonality

Polyclonal

Host

Goat

Species Reactivity

Expected from sequence similarity: Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Concentration

100ug specific antibody in 200ul (lot specific)

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Antibody/Peptide Pairs

CD3EAP peptide (MBS428549) is used for blocking the activity of CD3EAP antibody (MBS423351)

Molecular Weight

55,172 Da

OMIM

107325

Immunogen

Peptide with sequence C-PEDKTVKQEQINTEP, from the internal region of the protein sequence according to NP_036231.1.

Epitope

Internal region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-CD3EAP antibody

Peptide ELISA (EIA)

Application Notes for anti-CD3EAP antibody

Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments in nuclear lysates of cell lines HeLa, Jurkat and A431 gave no specific signal but low background (at antibody concentration up to 1ug/ml).

Other Notes

Small volumes of anti-CD3EAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD3EAP. It may not necessarily be applicable to this product.

NCBI GI #

6912246

NCBI GeneID

10849

NCBI Accession #

NP_036231.1

UniProt Secondary Accession #

Q32N11; Q7Z5U2; Q9UPF6

UniProt Related Accession #

O15446

GenBank Nucleotide #

NM_012099.1

NCBI Official Full Name

DNA-directed RNA polymerase I subunit RPA34 isoform 2

NCBI Official Synonym Full Names

CD3e molecule associated protein

NCBI Official Symbol

CD3EAP

NCBI Official Synonym Symbols

ASE1; CAST; ASE-1; PAF49

UniProt Protein Name

DNA-directed RNA polymerase I subunit RPA34

UniProt Synonym Protein Names

A34.5; Antisense to ERCC-1 protein; ASE-1; CD3-epsilon-associated protein; CAST; CD3E-associated protein; RNA polymerase I-associated factor PAF49

UniProt Gene Name

CD3EAP

UniProt Synonym Gene Names

ASE1; CAST; PAF49; ASE-1; CAST; CD3E-associated protein

UniProt Entry Name

RPA34_HUMAN

NCBI Protein Information

DNA-directed RNA polymerase I subunit RPA34

UniProt Comments for CD3EAP

ASE-1: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Belongs to the eukaryotic RPA34 RNA polymerase subunit family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex; Nucleolus

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: chromosome; cytoplasm; DNA-directed RNA polymerase I complex; mitochondrion; nucleolus; nucleoplasm; nucleus; RNA polymerase I transcription factor complex

Molecular Function: DNA-directed RNA polymerase activity

Biological Process: positive regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; rRNA transcription; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on CD3EAP

1. There was no interaction between NFKB1 polymorphisms and PPP1R13L and CD3EAP and smoking status in relation to lung cancer risk

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD3EAP antibody

Products by Pathway	Pathway Diagram
B-WICH Complex Positively Regulates RRNA Expression Pathway antibodies	B-WICH Complex Positively Regulates RRNA Expression Pathway Diagram
Epigenetic Regulation Of Gene Expression Pathway antibodies	Epigenetic Regulation Of Gene Expression Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Negative Epigenetic Regulation Of RRNA Expression Pathway antibodies	Negative Epigenetic Regulation Of RRNA Expression Pathway Diagram
NoRC Negatively Regulates RRNA Expression Pathway antibodies	NoRC Negatively Regulates RRNA Expression Pathway Diagram
Positive Epigenetic Regulation Of RRNA Expression Pathway antibodies	Positive Epigenetic Regulation Of RRNA Expression Pathway Diagram
RNA Polymerase I Chain Elongation Pathway antibodies	RNA Polymerase I Chain Elongation Pathway Diagram
RNA Polymerase I Promoter Clearance Pathway antibodies	RNA Polymerase I Promoter Clearance Pathway Diagram
RNA Polymerase I Promoter Escape Pathway antibodies	RNA Polymerase I Promoter Escape Pathway Diagram
RNA Polymerase I Transcription Pathway antibodies	RNA Polymerase I Transcription Pathway Diagram

Diseases associated with anti-CD3EAP antibody

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>8 publications with CD3EAP and Lung Diseases
Lung Neoplasms Antibodies	>7 publications with CD3EAP and Lung Neoplasms
Cardiovascular Diseases Antibodies	>3 publications with CD3EAP and Cardiovascular Diseases
Inflammation Antibodies	>3 publications with CD3EAP and Inflammation
Neoplasms, Experimental Antibodies	>1 publications with CD3EAP and Neoplasms, Experimental
Poisoning Antibodies	>1 publications with CD3EAP and Poisoning

Organs/Tissues associated with anti-CD3EAP antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>11 publications with CD3EAP and Lung
Bone Antibodies	>2 publications with CD3EAP and Bone
Skin Antibodies	>2 publications with CD3EAP and Skin
Brain Antibodies	>2 publications with CD3EAP and Brain
Vascular Antibodies	>1 publications with CD3EAP and Vascular
Pancreas Antibodies	>1 publications with CD3EAP and Pancreas
Eye Antibodies	>1 publications with CD3EAP and Eye