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JUND Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423387

MBS423387 is an antibody targeting JUND. Also known as Goat anti-JUND Antibody. Reactive in Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
JUND, Polyclonal Antibody
Full Product Name
Goat anti-JUND Antibody
Product Gene Name
anti-JUND antibody
Product Synonym Names
JUND; jun D proto-oncogene; JunD-FL isoform; transcription factor jun-D; JUND antibody; jun D proto-oncogene antibody; JunD-FL isoform antibody; transcription factor jun-D antibody
Immunogen Sequence
CQLLPQHQVP AY
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
JUND peptide (MBS428015) is used for blocking the activity of JUND antibody (MBS423387)
Molecular Weight
35,174 Da
OMIM
165162
Immunogen
Peptide with sequence CQLLPQHQVPAY, from the C Terminus of the protein sequence according to NP_005345.3.
Epitope
C Terminus
Note
This antibody is expected NOT to cross-react with Jun oncogen (NP_002219.1, GeneID 3725)
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-JUND antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-JUND antibody
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 40kDa band observed in nuclear lysates of cell line NIH3T3 (calculated MW of 35.2kDa according to NP_005345.3). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Short and Pfarr,J Biol Chem.2002 Sep 6;277(36): 32697-705. PMID: 12105216). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-JUND antibody

(1ug/ml) staining of NIH3T3 nuclear lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-JUND Polyclonal Antibody – Cat# MBS423387

Other Notes

Small volumes of anti-JUND antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for JUND. It may not necessarily be applicable to this product.

NCBI GI #
102469037
NCBI GeneID
3727
NCBI Accession #
NP_005345.3
UniProt Secondary Accession #
Q53EK9
UniProt Related Accession #
P17535
GenBank Nucleotide #
NM_005354.5
NCBI Official Full Name
transcription factor jun-D isoform JunD-FL
NCBI Official Synonym Full Names
JunD proto-oncogene, AP-1 transcription factor subunit
NCBI Official Symbol
JUND
NCBI Official Synonym Symbols
AP-1
UniProt Protein Name
Transcription factor jun-D
Protein Family
Transcription factor
UniProt Gene Name
JUND
UniProt Entry Name
JUND_HUMAN
NCBI Protein Information
transcription factor jun-D

NCBI Summary for JUND

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013]
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UniProt Comments for JUND

JunD: Transcription factor binding AP-1 sites. Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation. Belongs to the bZIP family. Jun subfamily.

Protein type: Motility/polarity/chemotaxis; Transcription factor

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: chromatin; nuclear chromatin; nucleus; transcription factor complex

Molecular Function: enzyme binding; ligand-dependent nuclear receptor binding; protein binding; transcription coactivator activity; transcription factor binding

Biological Process: aging; cellular response to hormone stimulus; circadian rhythm; negative regulation of transcription from RNA polymerase II promoter; osteoblast development; positive regulation of cell differentiation; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; response to cAMP; response to cytokine stimulus; response to drug; response to light stimulus; response to lipopolysaccharide; response to mechanical stimulus; response to peptide hormone stimulus; response to radiation; transcription from RNA polymerase II promoter
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Research Articles on JUND

1. miR-494 is a novel regulator of HNPC apoptosis induced by TNF-alpha

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-JUND antibody

 Reference Product  PubMed Publications
 FOS antibody  >516 publications with JUND and FOS
 FOSB antibody  >182 publications with JUND and FOSB
 MEN1 antibody  >51 publications with JUND and MEN1
 FOSL2 antibody  >44 publications with JUND and FOSL2
 CDK4 antibody  >14 publications with JUND and CDK4
 MAPK8 antibody  >13 publications with JUND and MAPK8
 FOSL1 antibody  >8 publications with JUND and FOSL1
 EP300 antibody  >3 publications with JUND and EP300

Pathways associated with anti-JUND antibody

 Products by Pathway  Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Corticotropin-releasing Hormone Pathway antibodies  Corticotropin-releasing Hormone Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Hypertrophy Model Pathway antibodies  Hypertrophy Model Pathway Diagram
 Integrated Pancreatic Cancer Pathway antibodies  Integrated Pancreatic Cancer Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Oncostatin M Signaling Pathway antibodies  Oncostatin M Signaling Pathway Diagram

Diseases associated with anti-JUND antibody

 Disease Name  Pubmed Publications
 Cell Transformation, Neoplastic Antibodies  >50 publications with JUND and Cell Transformation, Neoplastic
 Necrosis Antibodies  >47 publications with JUND and Necrosis
 Inflammation Antibodies  >41 publications with JUND and Inflammation
 Liver Diseases Antibodies  >33 publications with JUND and Liver Diseases
 Disease Models, Animal Antibodies  >30 publications with JUND and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >29 publications with JUND and Cardiovascular Diseases
 Fibrosis Antibodies  >25 publications with JUND and Fibrosis
 Breast Neoplasms Antibodies  >22 publications with JUND and Breast Neoplasms
 Kidney Diseases Antibodies  >21 publications with JUND and Kidney Diseases
 Neoplasms, Experimental Antibodies  >21 publications with JUND and Neoplasms, Experimental

Organs/Tissues associated with anti-JUND antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >126 publications with JUND and Blood
 Brain Antibodies  >108 publications with JUND and Brain
 Bone Antibodies  >71 publications with JUND and Bone
 Liver Antibodies  >58 publications with JUND and Liver
 Muscle Antibodies  >46 publications with JUND and Muscle
 Lung Antibodies  >42 publications with JUND and Lung
 Vascular Antibodies  >38 publications with JUND and Vascular
 Skin Antibodies  >37 publications with JUND and Skin
 Kidney Antibodies  >30 publications with JUND and Kidney
 Heart Antibodies  >25 publications with JUND and Heart
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