• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SERPINB1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423467

MBS423467 is an antibody targeting SERPINB1. Also known as Goat anti-SERPINB1 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SERPINB1, Polyclonal Antibody
Full Product Name
Goat anti-SERPINB1 Antibody
Product Gene Name
Product Synonym Names
Goat Anti-SERPINB1 (aa130-143) Antibody; SERPINB1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; EI; ELANH2; LEI; M/NEI; MNEI; PI-2; PI2; leukocyte elastase inhibitor; peptidase inhibitor 2; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) prot; SERPINB1 antibody; serpin peptidase inhibitor; clade B (ovalbumin); member 1 antibody; EI antibody; ELANH2 antibody; LEI antibody; M/NEI antibody; MNEI antibody; PI-2 antibody; PI2 antibody; leukocyte elastase inhibitor antibody; peptidase inhibitor 2 antibody; protease inhibitor 2 (anti-elastase); monocyte/neutrophil derived antibody; serine (or cysteine) prot antibody
Immunogen Sequence
EVHSRFQSLN ADINKR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
SERPINB1 peptide (MBS428431) is used for blocking the activity of SERPINB1 antibody (MBS423467)
Molecular Weight
26,073 Da
OMIM
130135
Immunogen
Peptide with sequence C-EVHSRFQSLNADINKR, from the internal region of the protein sequence according to NP_109591.1.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-SERPINB1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-SERPINB1 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 43kDa band observed in lysates of cell line A549 (calculated MW of 42.7kDa according to NP_109591.1). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-SERPINB1 antibody

(1ug/ml) staining of A549 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-SERPINB1 Polyclonal Antibody – Cat# MBS423467

Other Notes

Small volumes of anti-SERPINB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SERPINB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
leukocyte elastase inhibitor
NCBI Official Synonym Full Names
serpin family B member 1
NCBI Official Symbol
SERPINB1
NCBI Official Synonym Symbols
EI; LEI; PI2; MNEI; PI-2; HEL57; M/NEI; ELANH2; HEL-S-27
UniProt Protein Name
Leukocyte elastase inhibitor
UniProt Synonym Protein Names
Monocyte/neutrophil elastase inhibitor; EI; M/NEI; Peptidase inhibitor 2; PI-2; Serpin B1
UniProt Gene Name
SERPINB1
UniProt Synonym Gene Names
ELANH2; MNEI; PI2; LEI; EI; M/NEI; PI-2
UniProt Entry Name
ILEU_HUMAN
NCBI Protein Information
leukocyte elastase inhibitor

NCBI Summary for SERPINB1

The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Show more

UniProt Comments for SERPINB1

SERPINB1: Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Belongs to the serpin family. Ov-serpin subfamily.

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: cytoplasm; extracellular space; membrane

Molecular Function: serine-type endopeptidase inhibitor activity
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SERPINB1 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000