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EGFL7 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423575

MBS423575 is an antibody targeting EGFL7. Also known as Goat anti-EGFL7 Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EGFL7, Polyclonal Antibody
Full Product Name
Goat anti-EGFL7 Antibody
Product Gene Name
Product Synonym Names
EGFL7; EGF-like-domain, multiple 7; NEU1; RP11-251M1.2; VE-STATIN; ZNEU1; EGF-like protein 7; NOTCH4-like protein; epidermal growth factor-like protein 7; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7; vascul; EGFL7 antibody; EGF-like-domain; multiple 7 antibody; NEU1 antibody; RP11-251M1.2 antibody; VE-STATIN antibody; ZNEU1 antibody; EGF-like protein 7 antibody; NOTCH4-like protein antibody; epidermal growth factor-like protein 7 antibody; multiple EGF-like domains protein 7 antibody; multiple epidermal growth factor-like domains protein 7 antibody; antibody
Immunogen Sequence
HGDPVSESFV QR
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
EGFL7 peptide (MBS428724) is used for blocking the activity of EGFL7 antibody (MBS423575)
Molecular Weight
29,618 Da
OMIM
608582
Immunogen
Peptide with sequence C-HGDPVSESFVQR, from the internal region of the protein sequence according to NP_057299.1.
Epitope
Internal region
Note
The immunizing peptide represents the N terminus of the mature protein. Reported variants represent identical protein: NP_057299.1, NP_958854.1.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-EGFL7 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-EGFL7 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 26-27kDa band observed in Human Heart, Kidney and Lung lysates (calculated MW of 29.6kDa according to NP_057299.1). The observed molecular weight corresponds to the mature form (calc. MW 27.1kDa without its 23aa signal peptide). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-EGFL7 antibody

(1ug/ml) staining of Heart (A), Kidney (B) and Lung (C) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-EGFL7 Polyclonal Antibody – Cat# MBS423575

Other Notes

Small volumes of anti-EGFL7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EGFL7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
epidermal growth factor-like protein 7
NCBI Official Synonym Full Names
EGF like domain multiple 7
NCBI Official Symbol
EGFL7
NCBI Official Synonym Symbols
NEU1; ZNEU1; VE-STATIN
UniProt Protein Name
Epidermal growth factor-like protein 7
UniProt Synonym Protein Names
Multiple epidermal growth factor-like domains protein 7; Multiple EGF-like domains protein 7; NOTCH4-like protein; Vascular endothelial statin; VE-statin; Zneu1
UniProt Gene Name
EGFL7
UniProt Synonym Gene Names
MEGF7; EGF-like protein 7; Multiple EGF-like domains protein 7; VE-statin
UniProt Entry Name
EGFL7_HUMAN
NCBI Protein Information
epidermal growth factor-like protein 7

NCBI Summary for EGFL7

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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UniProt Comments for EGFL7

EGFL7: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular matrix; extracellular region; extracellular space

Molecular Function: calcium ion binding

Biological Process: angiogenesis; blood vessel development; cell adhesion; negative regulation of Notch signaling pathway; positive regulation of endothelial cell proliferation; vasculogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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