• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

ITGA3 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423620

MBS423620 is an antibody targeting ITGA3. Also known as Goat anti-ITGA3 (isoform a) Antibody. Reactive in Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse, Pig, Cow. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ITGA3, Polyclonal Antibody
Full Product Name
Goat anti-ITGA3 (isoform a) Antibody
Product Gene Name
Product Synonym Names
ITGA3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); CD49C; GAP-B3; GAPB3; ILNEB; MSK18; VCA-2; VL3A; VLA3a; CD49 antigen-like family member C; FRP-2; VLA-3 subunit alpha; antigen identified by monoclonal antibody J143; galactoprot; ITGA3 antibody; integrin; alpha 3 (antigen CD49C; alpha 3 subunit of VLA-3 receptor) antibody; CD49C antibody; GAP-B3 antibody; GAPB3 antibody; ILNEB antibody; MSK18 antibody; VCA-2 antibody; VL3A antibody; VLA3a antibody; CD49 antigen-like family member C antibody; FRP-2 antibody; VLA-3 subunit alpha antibody; antigen identified by monoclonal antibody J143 antibody; galactoprot antibody; ITGA3 (isoform a)
Immunogen Sequence
KSQPSETERL TDD
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human, Mouse; Expected from sequence similarity: Human, Mouse, Pig, Cow
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
ITGA3 peptide (MBS428737) is used for blocking the activity of ITGA3 antibody (MBS423620)
OMIM
605025
Immunogen
Peptide with sequence C-KSQPSETERLTDD, from the C Terminus of the protein sequence according to NP_002195.1.
Epitope
C Terminus
Note
This antibody is expected to recognize reported isoform a (NP_002195.1).
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ITGA3 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-ITGA3 antibody
Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 100kDa band observed in Human and Mouse Heart lysates (calculated MW of 117kDa according to NP_002195.1). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-ITGA3 antibody

(1ug/ml) staining of Human (A) and Mouse (B) Heart lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-ITGA3 Polyclonal Antibody – Cat# MBS423620

Other Notes

Small volumes of anti-ITGA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ITGA3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
integrin alpha-3 preproprotein
NCBI Official Synonym Full Names
integrin subunit alpha 3
NCBI Official Symbol
ITGA3
NCBI Official Synonym Symbols
VL3A; CD49C; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
UniProt Protein Name
Integrin alpha-3
UniProt Synonym Protein Names
CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3
Protein Family
UniProt Gene Name
ITGA3
UniProt Synonym Gene Names
MSK18; GAPB3
UniProt Entry Name
ITA3_HUMAN
NCBI Protein Information
integrin alpha-3

NCBI Summary for ITGA3

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
Show more

UniProt Comments for ITGA3

Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000