Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

SPOT14 (THRSP) Antibody

Name: THRSP Antibody; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS423725
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS423725

MBS423725 is an antibody targeting THRSP. Also known as Goat anti-SPOT14 Antibody. Reactive in Human. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

SPOT14 (THRSP), Antibody

Full Product Name

Goat anti-SPOT14 Antibody

Product Gene Name

anti-THRSP antibody

Product Synonym Names

THRSP; thyroid hormone responsive (SPOT14 homolog, rat) ; MGC21659; S14; SPOT14; spot 14 protein; thyroid hormone responsive SPOT14; thyroid hormone-inducible hepatic protein; thyroid hormone-responsive protein

Species Reactivity

Human

Form/Format

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Purity/Purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Preparation and Storage

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Molecular Weight

16,561 Da

OMIM

601926

3D Structure

ModBase 3D Structure for Q92748

Immunogen Sequence

Peptide with sequence C-SEENGTAETEEVED, from the internal region of the protein sequence according to NP_003242.1.

Peptide Sequence + C

C-SEENGTAETEEVED

Epitope

Internal Region

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-THRSP antibody

Peptide ELISA (EIA), Flow Cytometry (FC/FACS)

Application Notes for anti-THRSP antibody

Pep-ELISA: antibody detection limit dilution 1:4000.
FC/FACS: Flow cytometric analysis of A431 cells. Recommended concentration: 10ug/ml.

Other Notes

Small volumes of anti-THRSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for THRSP. It may not necessarily be applicable to this product.

NCBI GI #

4507497

NCBI GeneID

7069

NCBI Accession #

NP_003242.1

UniProt Primary Accession #

Q92748

UniProt Secondary Accession #

B2R4W7

UniProt Related Accession #

Q92748

GenBank Nucleotide #

NM_003251.3

NCBI Official Full Name

thyroid hormone-inducible hepatic protein

NCBI Official Synonym Full Names

thyroid hormone responsive

NCBI Official Symbol

THRSP

NCBI Official Synonym Symbols

S14; Lpgp; THRP; LPGP1; SPOT14

UniProt Protein Name

Thyroid hormone-inducible hepatic protein

UniProt Synonym Protein Names

Spot 14 protein; S14; SPOT14

Protein Family

Thyroid hormone-inducible hepatic protein

UniProt Gene Name

THRSP

UniProt Synonym Gene Names

S14; SPOT14

NCBI Protein Information

thyroid hormone-inducible hepatic protein

NCBI Summary for THRSP

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism. [provided by RefSeq, Jul 2008]

UniProt Comments for THRSP

Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA (). May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.

Research Articles on THRSP

1. The results of the present study indicated that Spot14/S14R were differently expressed in MSC adipogenesis in AIS patients, and they may be important in the abnormal adipogenic differentiation in AIS.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-THRSP antibody

Reference Product	PubMed Publications
FASN antibody	>27 publications with THRSP and FASN
NR1I3 antibody	>1 publications with THRSP and NR1I3
SYT12 antibody	>1 publications with THRSP and SYT12

Pathways associated with anti-THRSP antibody

Products by Pathway	Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway antibodies	Import Of Palmitoyl-CoA Into The Mitochondrial Matrix Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram

Diseases associated with anti-THRSP antibody

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>46 publications with THRSP and Fatty Liver
Carcinoma Antibodies	>7 publications with THRSP and Carcinoma
Liver Diseases Antibodies	>6 publications with THRSP and Liver Diseases
Insulin Resistance Antibodies	>6 publications with THRSP and Insulin Resistance
Liver Neoplasms Antibodies	>5 publications with THRSP and Liver Neoplasms
Inflammation Antibodies	>5 publications with THRSP and Inflammation
Weight Loss Antibodies	>4 publications with THRSP and Weight Loss
Adenocarcinoma Antibodies	>4 publications with THRSP and Adenocarcinoma
Weight Gain Antibodies	>4 publications with THRSP and Weight Gain
Non-alcoholic Fatty Liver Disease Antibodies	>3 publications with THRSP and Non-alcoholic Fatty Liver Disease

Organs/Tissues associated with anti-THRSP antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>104 publications with THRSP and Liver
Thyroid Antibodies	>95 publications with THRSP and Thyroid
Adipose Tissue Antibodies	>40 publications with THRSP and Adipose Tissue
Muscle Antibodies	>18 publications with THRSP and Muscle
Brain Antibodies	>9 publications with THRSP and Brain
Kidney Antibodies	>6 publications with THRSP and Kidney
Heart Antibodies	>5 publications with THRSP and Heart
Intestine Antibodies	>2 publications with THRSP and Intestine
Lung Antibodies	>2 publications with THRSP and Lung
Bone Antibodies	>2 publications with THRSP and Bone