Phospholipid Scramblase 1 (PLSCR1) ELISA Kit for Rat

Name: Rat PLSCR1 ELISA Kit; Phospholipid Scramblase 1; MyBioSource
Brand: MyBioSource
SKU: MBS042653
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS042653

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of PLSCR1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates,… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Phospholipid Scramblase 1 (PLSCR1), ELISA Kit

Full Product Name

Rat Phospholipid Scramblase 1 ELISA Kit

Product Gene Name

PLSCR1 elisa kit

Species Reactivity

Rat

Assay Type

Sandwich

Samples

Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

Detection Range

0.5 ng/ml - 16 ng/ml.

Sensitivity

0.1 ng/ml.

Specificity

No significant cross-reactivity or interference between this analyte and analogues is observed.

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

35,049 Da

Chromosome Location

Chromosome: 3; NC_000003.11 (146232967..146262628, complement). Location: 3q23

OMIM

604170

3D Structure

ModBase 3D Structure for O15162

Other Notes

Small volumes of PLSCR1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLSCR1 purchase

MBS042653 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Phospholipid Scramblase 1 (PLSCR1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLSCR1. The ELISA analytical biochemical technique of the MBS042653 kit is based on PLSCR1 antibody-PLSCR1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLSCR1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLSCR1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for PLSCR1. It may not necessarily be applicable to this product.

NCBI GI #

10863877

NCBI GeneID

5359

NCBI Accession #

NP_066928.1

UniProt Primary Accession #

O15162

UniProt Secondary Accession #

B2R8H8

UniProt Related Accession #

O15162

GenBank Nucleotide #

NM_021105.2

NCBI Official Full Name

phospholipid scramblase 1

NCBI Official Synonym Full Names

phospholipid scramblase 1

NCBI Official Symbol

PLSCR1

NCBI Official Synonym Symbols

MMTRA1B

UniProt Protein Name

Phospholipid scramblase 1

UniProt Synonym Protein Names

Ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1b

Protein Family

Phospholipid scramblase

UniProt Gene Name

PLSCR1

UniProt Synonym Gene Names

PL scramblase 1

UniProt Entry Name

PLS1_HUMAN

NCBI Protein Information

phospholipid scramblase 1; PL scramblase 1; erythrocyte phospholipid scramblase; ca(2+)-dependent phospholipid scramblase 1

UniProt Comments for PLSCR1

PLSCR1: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.

Protein type: Membrane protein, integral; Calcium-binding

Chromosomal Location of Human Ortholog: 3q23

Cellular Component: extracellular matrix; Golgi apparatus; membrane; integral to plasma membrane; plasma membrane; nucleolus; cytosol; nucleus; lipid raft

Molecular Function: phospholipid scramblase activity; protein binding; enzyme binding; DNA binding; calcium ion binding; SH3 domain binding; CD4 receptor binding; epidermal growth factor receptor binding

Biological Process: platelet activation; negative regulation of viral genome replication; apoptosis; positive regulation of innate immune response; acute-phase response; positive regulation of transcription from RNA polymerase II promoter; phospholipid scrambling; defense response to virus; regulation of mast cell activation; phosphatidylserine biosynthetic process

Research Articles on PLSCR1

1. Phospholipid scramblase 1 expression is enhanced in patients with antiphospholipid syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PLSCR1 elisa kit

Reference Product	PubMed Publications
SRC elisa kit	>8 publications with PLSCR1 and SRC
CD4 elisa kit	>1 publications with PLSCR1 and CD4
OXSR1 elisa kit	>1 publications with PLSCR1 and OXSR1
ITPR1 elisa kit	>1 publications with PLSCR1 and ITPR1
PRTN3 elisa kit	>1 publications with PLSCR1 and PRTN3
SHC1 elisa kit	>1 publications with PLSCR1 and SHC1
BACE1 elisa kit	>1 publications with PLSCR1 and BACE1

Pathways associated with PLSCR1 elisa kit

Products by Pathway	Pathway Diagram
EGFR1 Signaling Pathway antibodies	EGFR1 Signaling Pathway Diagram

Diseases associated with PLSCR1 elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>11 publications with PLSCR1 and Neoplasms
Carcinoma Antibodies	>5 publications with PLSCR1 and Carcinoma
Cardiovascular Diseases Antibodies	>3 publications with PLSCR1 and Cardiovascular Diseases
Liver Diseases Antibodies	>3 publications with PLSCR1 and Liver Diseases
Inflammation Antibodies	>3 publications with PLSCR1 and Inflammation
Hepatitis Antibodies	>3 publications with PLSCR1 and Hepatitis
Carcinoma, Hepatocellular Antibodies	>2 publications with PLSCR1 and Carcinoma, Hepatocellular
Necrosis Antibodies	>2 publications with PLSCR1 and Necrosis
Drug Toxicity Antibodies	>2 publications with PLSCR1 and Drug Toxicity
Liver Neoplasms Antibodies	>2 publications with PLSCR1 and Liver Neoplasms

Organs/Tissues associated with PLSCR1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>22 publications with PLSCR1 and Blood
Bone Antibodies	>5 publications with PLSCR1 and Bone
Liver Antibodies	>5 publications with PLSCR1 and Liver
Bone Marrow Antibodies	>4 publications with PLSCR1 and Bone Marrow
Adipose Tissue Antibodies	>3 publications with PLSCR1 and Adipose Tissue
Connective Tissue Antibodies	>3 publications with PLSCR1 and Connective Tissue
Brain Antibodies	>2 publications with PLSCR1 and Brain
Muscle Antibodies	>2 publications with PLSCR1 and Muscle
Vascular Antibodies	>2 publications with PLSCR1 and Vascular
Kidney Antibodies	>2 publications with PLSCR1 and Kidney