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Gp120 (Hxbc2) (HIV-1/Clade B) (gp120) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS434048

Introduction: Envelope glycoprotein GP120 (or gp120) is a glycoprotein exposed on the surface of the HIV envelope. The 120 in its name comes from its molecular weight of 120. Gp120 is essential for virus entry into cells as it plays a vital role in attachment… More details

$400 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
gp120 (HXBc2) (HIV-1/Clade B), Recombinant Protein
Full Product Name
gp120 (HXBc2) (HIV-1/Clade B) (aa 34-518)
Product Gene Name
Product Synonym Names
gp120 (HXBc2) (HIV-1/Clade B) (aa 34-518); glycosylated recombinant protein; gp120 (HXBC2) (Clade B); gp120 (HXBc2) (HIV-1/Clade B) (aa 34-518), glycosylated recombinant protein
Sequence
WVTVYYGVPV WKEAT TTL FCASDAKAYD TEVHNVWATH ACVPTDPNPQ EVVLVNVTEN FNMWKNDMV EQMHEDIISL WDQSLKPC VKLTPLCVSL KCTDLKNDTN TNSSSGRMIM EKGEIKNCS FNI STSI RGKVQKEYAF FYKLDI I PIDNDTTSYK LTSCNTSVIT QA CPKVSFEPIP IHYCAPAGFA ILKCNNKTFN GTGPCTNVST VQCTHGIRPV VS TQLLLNGSLA EEEVVI RSVNFTDNAK TI I VQLN TSVEINCTRP NNNTRKRIRI QRGPGRAFVT IGKIGNMRQA HCNISRAKWN NTLKQIASKL REQFGNNKTI I FKQSSGGDPE IVTH SFNCGGEFFY CNSTQLFNST WFNSTWSTEG SNNTEGSDTI TLPCRIKQII NMWQKVGKAM YAPPISGQIR CSSNITGLLL TRDGG NSNNESEI FRPGGGDMRD NWRSELYKYK VVKIEPLGVA PTKAKRRVVQ REKRAVGHHH HHH
Purity/Purification
> 95% purity (SDS PAGE).
Concentration
1 ug/ul in PBS (lot specific)
Preparation and Storage
Long term storage at -20°C or -70°C ; Stable for 3 months from date of receipt when kept at 4°C.
Endotxin Level
<0.01 EU per 1 ug of the protein by LAL test.
Applications Tested/Suitable for gp120 recombinant protein
Western Blot (WB), ELISA (EIA), HIV-1 entry inhibition,etc.

SDS-PAGE (SDS) of gp120 recombinant protein

SDS-PAGE: purified HIV-1 gp120 (HXBc2) (Clade B) protein
gp120 Recombinant Protein – Cat# MBS434048

Other Notes

Small volumes of gp120 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for gp120 purchase

MBS434048 is a recombinant protein targeting gp120. Also known as gp120 (HXBc2) (HIV-1/Clade B) (aa 34-518).

Additional Details

NCBI/Uniprot data below describe general gene information for gp120. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Secondary Accession #
NCBI Official Full Name
Human immunodeficiency virus type 1 (HXB2), complete genome; HIV1/HTLV-III/LAV reference genome
UniProt Protein Name
Protein Nef
UniProt Synonym Protein Names
3'ORF; Negative factor; F-protein
UniProt Gene Name
nef
UniProt Entry Name
NEF_HV1H2

UniProt Comments for gp120

Factor of infectivity and pathogenicity, required for optimal virus replication (). Alters numerous pathways of T-lymphocytes function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity (PubMed:9450757). Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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