Interferon Alpha-2a (IFN alpha-2a) Human Active Protein

Description: Recombinant human IFN alpha-2a produced in Yeast is a single, non-glycosylated, polypeptide chain containing 165 amino acids, two pairs of disulfide bonds and having a molecular mass of approximately 19.2kD.
Introduction: Human Interferon alpha-2a is a single polypeptide chain of 165 amino acids residues, containing 4 Cys to form two disulfide bonds at positions of Cys 1- Cys 98 and Cys 29-Cys 138, and it has a molecular mass of approximately 19.2kD. IFN can exert certain cell activities through binding to specific cell surface receptors, as firstly induce to develop special proteins, such as protein kinase and 2', 5'-oligo polyadenylic acid synthase etc. The unique character of two enzymes is that they can be activated respectively by double chains RNA to produce the effect of self-phosphorylation. INF can also enhance phagocytosis activity of macrophage and special toxicity of lymphocyte to target cells to cause immunoloregulation. Its biological effects contains: (1) Anti-virus: INF alpha has broad-spectrum anti-virus effect; (2) Cytostatic effect to certain cells; (3) Immunoloregulation effect: accelerate the expression of MHC antigen by most cell and active NK cell and CTL. (4) Repress and kill tumor cells: INF-alpha kill the tumor cells through accelerating the immunological function and enhancing the killing ability of macrophage, NK and CTL.

Small volumes of IFN alpha-2a active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS434176 is an active protein targeting IFN alpha-2a. Also known as Human Interferon alpha-2a (IFN alpha-2a), yeast. Host: Yeast.