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DR5/TNFRSF10B Antibody – Rabbit Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435193

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an… More details

$435 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DR5/TNFRSF10B, Monoclonal Antibody
Full Product Name
DR5/TNFRSF10B Rabbit mAb
Product Synonym Gene Name
DR5; TNFRSF10B; CD262; KILLER; TRAILR2; TRICK2; ZTNFR9
Product Synonym Names
Tumor necrosis factor receptor superfamily member 10B
Clonality
Monoclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.
Molecular Weight
48kDa
3D Structure
ModBase 3D Structure for P61964
Source Note
This monoclonal antibody is produced by immunizing animals with a polypeptide corresponding to DR5/TNFRSF10B protein.
Applications Tested/Suitable for anti-DR5/TNFRSF10B antibody
Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-DR5/TNFRSF10B antibody
WB: 1:500-1:1000
FC/FACS 1:100-1:200

Western Blot (WB) of anti-DR5/TNFRSF10B antibody

Rabbit Anti-DR5/TNFRSF10B Monoclonal Antibody – Cat# MBS435193

Flow Cytometry (FC/FACS) of anti-DR5/TNFRSF10B antibody

Rabbit Anti-DR5/TNFRSF10B Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS435193

Other Notes

Small volumes of anti-DR5/TNFRSF10B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DR5/TNFRSF10B purchase

MBS435193 is an antibody targeting DR5/TNFRSF10B. Also known as DR5/TNFRSF10B Rabbit mAb. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DR5/TNFRSF10B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
WD repeat-containing protein 5
NCBI Official Synonym Full Names
WD repeat domain 5
NCBI Official Symbol
WDR5
NCBI Official Synonym Symbols
SWD3; BIG-3; CFAP89
UniProt Protein Name
WD repeat-containing protein 5
UniProt Synonym Protein Names
BMP2-induced 3-kb gene protein
UniProt Gene Name
WDR5
UniProt Synonym Gene Names
BIG3
NCBI Protein Information
WD repeat-containing protein 5

NCBI Summary for DR5/TNFRSF10B

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
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UniProt Comments for DR5/TNFRSF10B

Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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