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OST48/DDOST Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435254

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
OST48/DDOST, Monoclonal Antibody
Full Product Name
OST48/DDOST Mouse mAb
Product Gene Name
Product Synonym Names
advanced glycation end-product receptor 1; advanced glycation endproduct receptor 1; AGER1; DDOST 48 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); dolichyl-diphosphooligosaccharide-protein glycosyltransferase; dolichyl-diphosphooligosaccharide-protein glycotransf; dolichyl-diphosphooligosaccharide-protein glycotransferase; OKSWcl45; oligosaccharyl transferase 48 kDa subunit; oligosaccharyltransferase 48 kDa subunit; oligosaccharyltransferase subunit 48; OST; OST48; WBP1
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Homo sapiens (Human)
Preparation and Storage
Store at -20°C. Stable for one year from the date of shipment.
3D Structure
ModBase 3D Structure for P39656
Source Note
This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to OST48 protein.

Product Categories/Family for anti-OST48/DDOST antibody

Applications Tested/Suitable for anti-OST48/DDOST antibody
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Application Notes for anti-OST48/DDOST antibody
WB: 1:1000-1:5000
IP: 10 tests
FC/FACS: 1:100-1:200

For Western blot, incubate membrane with diluted antibody in 5% w/v non fat dry milk, 1X TBS, 0.05% Tween -20 at 4°C with gentle shaking overnight

Western Blot (WB) of anti-OST48/DDOST antibody

Mouse Anti-OST48/DDOST Monoclonal Antibody – Cat# MBS435254

Immunoprecipitation (IP) of anti-OST48/DDOST antibody

Mouse Anti-OST48/DDOST Monoclonal Antibody, Immunoprecipitation (IP) – Cat# MBS435254

Flow Cytometry (FC/FACS) of anti-OST48/DDOST antibody

Mouse Anti-OST48/DDOST Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS435254

Other Notes

Small volumes of anti-OST48/DDOST antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OST48/DDOST purchase

MBS435254 is an antibody targeting OST48/DDOST. Also known as OST48/DDOST Mouse mAb. Reactive in Homo sapiens (Human). Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for OST48/DDOST. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
NCBI Official Synonym Full Names
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
NCBI Official Symbol
DDOST
NCBI Official Synonym Symbols
OST; WBP1; AGER1; CDG1R; GATD6; OST48; OKSWcl45
UniProt Protein Name
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
UniProt Gene Name
DDOST
UniProt Synonym Gene Names
KIAA0115; OST48; DDOST 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit
NCBI Protein Information
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

NCBI Summary for OST48/DDOST

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
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UniProt Comments for OST48/DDOST

Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-OST48/DDOST antibody

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