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OSBPL3 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435271

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
OSBPL3, Monoclonal Antibody
Full Product Name
OSBPL3 Mouse mAb
Product Gene Name
Product Synonym Gene Name
ORP3; ORP-3; OSBP3
Product Synonym Names
Oxysterol-binding protein-related protein 3
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.
Molecular Weight
Predicted MW: 101kDa
3D Structure
ModBase 3D Structure for Q9H4L5
Source Note
This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to OSBPL3 protein.

Product Categories/Family for anti-OSBPL3 antibody

Applications Tested/Suitable for anti-OSBPL3 antibody
Western Blot (WB)
Application Notes for anti-OSBPL3 antibody
WB: 1:500-1:2000
FC/FACS 1:100-1:200

Western Blot (WB) of anti-OSBPL3 antibody

Mouse Anti-OSBPL3 Monoclonal Antibody – Cat# MBS435271

Other Notes

Small volumes of anti-OSBPL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OSBPL3 purchase

MBS435271 is an antibody targeting OSBPL3. Also known as OSBPL3 Mouse mAb. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for OSBPL3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
oxysterol-binding protein-related protein 3 isoform a
NCBI Official Synonym Full Names
oxysterol binding protein like 3
NCBI Official Symbol
OSBPL3
NCBI Official Synonym Symbols
ORP3; ORP-3; OSBP3
UniProt Protein Name
Oxysterol-binding protein-related protein 3
UniProt Gene Name
OSBPL3
UniProt Synonym Gene Names
KIAA0704; ORP3; OSBP3; ORP-3; OSBP-related protein 3
NCBI Protein Information
oxysterol-binding protein-related protein 3

UniProt Comments for OSBPL3

Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes (PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments (PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology (PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion (PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3 (PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol (PubMed:17428193).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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