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Immunity-Related Gtpase Family M Protein (IRGM1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS435452

Immunity-related GTPase family M protein, also known as interferon-inducible protein 1, is an enzyme encoded by the IRGM gene. The protein is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response… More details

$265 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Immunity-related GTPase family M protein (IRGM1), Monoclonal Antibody
Full Product Name
Immunity-related GTPase family M protein Mouse mAb for Duck
Product Gene Name
Product Synonym Names
IFI1; LRG-47; LRG47; immunity related GTPase m1; Immunity-related GTPase family M protein; Immunity-related GTPase family M protein 1; immunity-related GTPase family; M; immunity-related GTPase family; M1; immunity-related GTPase M; interferon inducible protein 1; interferon-gamma-inducible GTPase Ifggd3 protein; Interferon-inducible GTPase 3; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47; LRG-47-like protein
Clonality
Monoclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Duck
Preparation and Storage
Store at -20 degree C. Stable for one year from the date of shipment.
Molecular Weight
Predicted MW: 47
Source Note
This monoclonal antibody is produced by immunizing mice with a polypeptide corresponding to immunity-related GTPase family M protein.

Product Categories/Family for anti-IRGM1 antibody

Applications Tested/Suitable for anti-IRGM1 antibody
Western Blot (WB)
Application Notes for anti-IRGM1 antibody
WB: 1:1000-1:5000

Western Blot (WB) of anti-IRGM1 antibody

Mouse Anti-IRGM1 Monoclonal Antibody – Cat# MBS435452

Other Notes

Small volumes of anti-IRGM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IRGM1 purchase

MBS435452 is an antibody targeting IRGM1. Also known as Immunity-related GTPase family M protein Mouse mAb for Duck. Reactive in Duck. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IRGM1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
immunity-related GTPase family M protein isoform 2
NCBI Official Synonym Full Names
immunity related GTPase M
NCBI Official Symbol
IRGM
NCBI Official Synonym Symbols
IFI1; IRGM1; LRG47; LRG-47
UniProt Protein Name
Immunity-related GTPase family M protein
UniProt Synonym Protein Names
Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47
UniProt Gene Name
IRGM
UniProt Synonym Gene Names
IFI1; IRGM1; LRG47; LRG-47
NCBI Protein Information
immunity-related GTPase family M protein

NCBI Summary for IRGM1

This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
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UniProt Comments for IRGM1

Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IRGM1 antibody

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