Rabbit Anti-CEACAM5 Polyclonal Antibody – Cat# MBS4381753

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CEA Rabbit Polyclonal Antibody.

Carcinoembryonic Antigen (CEA)/CD66 (CEACAM5) Antibody – Rabbit Polyclonal

Name: CEACAM5 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS4381753
Price: 280 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4381753

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not… More details

$280 / 0.02 mg (With BSA & Azide at 0.2mg/mL) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Carcinoembryonic Antigen (CEA)/CD66 (CEACAM5), Polyclonal Antibody

Full Product Name

Carcinoembryonic Antigen (CEA)/CD66 Rabbit Polyclonal Antibody

Product Gene Name

anti-CEACAM5 antibody

Product Synonym Names

Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)

Clonality

Polyclonal

Isotype

Rabbit/IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0. 05% BSA & 0. 05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration

Purified Ab with BSA and Azide at 200ug/ml
OR
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml (lot specific)

Preparation and Storage

Antibody with azide: store at 2 to 8 degree C
Antibody without azide: store at -20 to -80 degree C
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Molecular Weight

76,795 Da

OMIM

114890

3D Structure

ModBase 3D Structure for P06731

Immunogen

Human CEA protein

Cellular Localization

Cytoplasmic and luminal surface

Positive Control

MCF7 or 293T cells. Human colon carcinoma

Hu-chromosome Location

19q13.2

Unigene

709196

Applications Tested/Suitable for anti-CEACAM5 antibody

Immunohistochemistry-Formalin (IHC-F)

Application Notes for anti-CEACAM5 antibody

IHC (Formalin-fixed): 1-2ug/ml for 30 minutes at RT
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 45 minutes at 95 degree C followed by cooling at RT for 20 minutes)

Other Notes

Small volumes of anti-CEACAM5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CEACAM5 purchase

MBS4381753 is an antibody targeting CEACAM5. Also known as Carcinoembryonic Antigen (CEA)/CD66 Rabbit Polyclonal Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CEACAM5. It may not necessarily be applicable to this product.

NCBI GI #

317373456

NCBI GeneID

1048

NCBI Accession #

P06731.3

UniProt Primary Accession #

P06731

UniProt Secondary Accession #

H9KVA7

UniProt Related Accession #

P06731

NCBI Official Full Name

Carcinoembryonic antigen-related cell adhesion molecule 5

NCBI Official Synonym Full Names

carcinoembryonic antigen-related cell adhesion molecule 5

NCBI Official Symbol

CEACAM5

NCBI Official Synonym Symbols

CEA; CD66e

UniProt Protein Name

Carcinoembryonic antigen-related cell adhesion molecule 5

UniProt Synonym Protein Names

Carcinoembryonic antigen; CEA; Meconium antigen 100

Protein Family

Carcinoembryonic antigen-related cell adhesion molecule

UniProt Gene Name

CEACAM5

UniProt Synonym Gene Names

CEA; CEA

UniProt Entry Name

CEAM5_HUMAN

NCBI Protein Information

carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100

NCBI Summary for CEACAM5

Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009]

UniProt Comments for CEACAM5

CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family.

Protein type: Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.1-q13.2

Cellular Component: basolateral plasma membrane; integral to plasma membrane

Molecular Function: identical protein binding; protein homodimerization activity

Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis

Research Articles on CEACAM5

1. Results show that scFvs against HER-2/neu and carcinoembryonic antigen (CEA) were isolated.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CEACAM5 antibody

Reference Product	PubMed Publications
CEACAM6 antibody	>111 publications with CEACAM5 and CEACAM6
HNRNPM antibody	>3 publications with CEACAM5 and HNRNPM
RAB11A antibody	>1 publications with CEACAM5 and RAB11A
VPS33B antibody	>1 publications with CEACAM5 and VPS33B
VIPAR antibody	>1 publications with CEACAM5 and VIPAR

Diseases associated with anti-CEACAM5 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>14998 publications with CEACAM5 and Neoplasms
Adenocarcinoma Antibodies	>4740 publications with CEACAM5 and Adenocarcinoma
Liver Neoplasms Antibodies	>2545 publications with CEACAM5 and Liver Neoplasms
Lung Neoplasms Antibodies	>2167 publications with CEACAM5 and Lung Neoplasms
Neoplasms, Experimental Antibodies	>667 publications with CEACAM5 and Neoplasms, Experimental
Skin Neoplasms Antibodies	>556 publications with CEACAM5 and Skin Neoplasms
Necrosis Antibodies	>290 publications with CEACAM5 and Necrosis
Kidney Diseases Antibodies	>204 publications with CEACAM5 and Kidney Diseases
Fatty Liver Antibodies	>29 publications with CEACAM5 and Fatty Liver
Mammary Neoplasms, Animal Antibodies	>20 publications with CEACAM5 and Mammary Neoplasms, Animal

Organs/Tissues associated with anti-CEACAM5 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2356 publications with CEACAM5 and Lung
Stomach Antibodies	>1287 publications with CEACAM5 and Stomach
Thyroid Antibodies	>708 publications with CEACAM5 and Thyroid
Intestine Antibodies	>702 publications with CEACAM5 and Intestine
Pancreas Antibodies	>592 publications with CEACAM5 and Pancreas
Kidney Antibodies	>341 publications with CEACAM5 and Kidney
Ovary Antibodies	>337 publications with CEACAM5 and Ovary
Muscle Antibodies	>293 publications with CEACAM5 and Muscle
Brain Antibodies	>288 publications with CEACAM5 and Brain
Cervix Antibodies	>260 publications with CEACAM5 and Cervix