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Kappa Light Chain (B-Cell Marker) (IGKC) Antibody – Rabbit

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS439995

MBS439995 is an antibody targeting IGKC. Also known as Kappa Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone IGKC/1999R]. Reactive in Human. Host: Rabbit. More details

$280 / 0.02 mg (With BSA & Azide at 0.2mg/mL) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Kappa Light Chain (B-Cell Marker) (IGKC), Antibody
Full Product Name
Kappa Light Chain (B-Cell Marker) Recombinant Rabbit Monoclonal Antibody [Clone IGKC/1999R]
Product Gene Name
Product Synonym Names
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
200ug/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Specificity
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Preparation and Storage
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. ,Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Molecular Weight
25kDa
3D Structure
ModBase 3D Structure for P01601
Immunogen
Recombinant full-length human Ig kappa chain
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Cellular Localization
Cell Surface, cytoplasmic and secreted
Application Notes for anti-IGKC antibody
Western Blotting (0.5-1.0ug/ml); Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 min at RT); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)

Immunohistochemistry (IHC) of anti-IGKC antibody

Formalin-fixed, paraffin-embedded human Tonsil stained with Kappa Lt. Chain Rabbit Recombinant Monoclonal Antibody (IGKC /1999R).
Rabbit Anti-IGKC Antibody – Cat# MBS439995

SDS-Page of anti-IGKC antibody

SDS-PAGE Analysis of Purified Kappa Lt. Chain Rabbit Recombinant Monoclonal Antibody (IGKC /1999R).
Rabbit Anti-IGKC Antibody, SDS-Page – Cat# MBS439995

Product References and Citations for anti-IGKC antibody

1.Takahashi H et. al. Pathol Res Prac 189:300-311 (1993).2.Momose H et. al. Hum Pathol. 23:1115-1119 (1992).

Other Notes

Small volumes of anti-IGKC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IGKC. It may not necessarily be applicable to this product.

NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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