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EGFR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS440047

The EFGR family is a group of four structurally similar tyrosine kinases (EGFR, HER2/neu, ErbB-3, and ErbB-4) that dimerize on binding with a number of ligands, including EGF and transforming growth factor alpha (1&2). The 170 kDa epidermal growth factor… More details

$325 / 0.2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EGFR, Polyclonal Antibody
Full Product Name
EGFR (I12) Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, rat, human
Form/Format
200 ug/ml rabbit polyclonal IgG in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin.
Concentration
0.200 mg/ml (lot specific)
Specificity
Mouse, rat, and human EGFR
Preparation and Storage
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
Antibody/Peptide Pairs
EGFR peptide (MBS443047) is used for blocking the activity of EGFR antibody (MBS440047)
Molecular Weight
1,020 Da
3D Structure
ModBase 3D Structure for Q9P2Z9
Origin
EGFR (I12) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to a sequence near the carboxy terminus of human EGFR.
Immunogen
Synthetic peptide mapping to a sequence near the carboxy terminus of human EGFR.
Applications Tested/Suitable for anti-EGFR antibody
Western Blot (WB), Immunopreciptation (IP), Immunohistochemistry (IHC) Paraffin
Application Notes for anti-EGFR antibody
Western blot analysis of EGFR expression in A431 whole cell lysates.;

Western Blot (WB) of anti-EGFR antibody

Rabbit Anti-EGFR Polyclonal Antibody – Cat# MBS440047

Product References and Citations for anti-EGFR antibody

1. Franklin WA, Veve R, Hirsch FR, Helfrich BA, Bunn PA Jr. Epidermal growth factor receptor family in lung cancer and premalignancy. Semin Oncol 2002 Feb;29(1 Suppl 4):3-14.2. Yarden Y. The EGFR family and its ligands in human cancer, signalling mechanisms and therapeutic opportunities. Eur J Cancer 2001 Sep: 37 Suppl 4: S3-8.3. Reynolds F.H. Jr., Todaro G.J., Fryling C., and Stephenson J.R. Human transforming growth factors induces tyrosine phosphorylation of EGR receptors. Nature 1981 292: 259-262.4. Chen W.S., Lazar C.S., Poenie M, Tsien R.Y., Gill G.N., Rosenfeld M.G. Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature 1987 328: 820-823.

Other Notes

Small volumes of anti-EGFR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGFR purchase

MBS440047 is an antibody targeting EGFR. Also known as EGFR (I12) Antibody. Reactive in Mouse, rat, human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EGFR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
epidermal growth factor receptor, partial
UniProt Protein Name
Epidermal growth factor receptor
UniProt Synonym Protein Names
Epidermal growth factor receptor
UniProt Gene Name
c-erbB proto-oncogene
UniProt Entry Name
Q9P2Z9_HUMAN

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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