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CBL Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS440060

The proto-oncogene c-Cbl was initially identified as the cellular homologue of v-Cbl oncogene that induces pre-B cell lymphomas and myeloid leukemias in mice (1&2). In more recent studies Cbl has been shown to be a negative regulator of tyrosine kinase… More details

$325 / 0.2 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Cbl, Polyclonal Antibody
Full Product Name
Cbl (C14) Antibody
Product Gene Name
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse, rat, human
Form/Format
200 ug/ml rabbit polyclonal IgG in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin.
Concentration
0.200 mg/ml (lot specific)
Specificity
Mouse, rat, and human Cbl, reactive with normal and rearanged forms of Cbl
Preparation and Storage
Store this product at 4 degree C, do not freeze. The product is stable for one year from the date of shipment.
Antibody/Peptide Pairs
Cbl peptide (MBS443060) is used for blocking the activity of Cbl antibody (MBS440060)
Molecular Weight
51,473 Da
3D Structure
ModBase 3D Structure for O46034
Origin
Cbl (C14) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping to the carboxy terminal domain of human Cbl p120.
Immunogen
Synthetic peptide mapping to the carboxy terminal domain of human Cbl p120.
Applications Tested/Suitable for anti-Cbl antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-Cbl antibody
Recommended western blotting starting dilution 1:200.

Product References and Citations for anti-Cbl antibody

1. Liu YC, Altman A. 1998. Cbl: complex formation and functional implications. Cell Signal 10(6):377-385. 2. Miyake S, Lupher ML, Andoniou CE, Lill NL, Ota S, Douillard P, Rao N, Band H. 1997. The Cbl protooncogen product: from an enigmatic oncogene to center stage of signal transduction. Crit Rev Oncog 8(2-3):189-218.3. Rao N, Dodge I, Band H. 2002. The Cbl family of ubiquitin ligases: critical negative regulators of tyrosine kinase signaling in the immune system. J Leukoc Biol 71(5):753-763.4. Sanjay A, Horne WC, Baron R. 2001. The Cbl family: ubiquitin ligases regulating signaling by tyrosine kinase. Sci STKE 2001(110):PE40.

Other Notes

Small volumes of anti-Cbl antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cbl purchase

MBS440060 is an antibody targeting Cbl. Also known as Cbl (C14) Antibody. Reactive in Mouse, rat, human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Cbl. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
cbl
NCBI Official Symbol
Cbl
NCBI Official Synonym Symbols
anon-WO0118547.68; cbl; CBL; CG7037; CG7043; d-cbl; D-cbl; D-Cbl; D-Cbl L; D-cblL; D-cblS; dCbl; Dcbl; DCbl; DmelCG7037; Dv-cbl; Dv-Cbl; F165; v-Cbl
UniProt Protein Name
CG7037-PA, isoform A
UniProt Synonym Protein Names
CG7037-PA, isoform A
UniProt Gene Name
Cbl
UniProt Entry Name
O46034_DROME
NCBI Protein Information
CG7037 gene product from transcript CG7037-RB; CG7037-PA; CG7037-PB; Cbl; Cbl-PA; Cbl-PB; D-cblLONG; D-cblSHORT; cable

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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