Bone Morphogenetic Protein 15 (BMP15) ELISA Kit for Mouse

Name: Mouse BMP15 ELISA Kit; Bone Morphogenetic Protein 15; MyBioSource
Brand: MyBioSource
SKU: MBS044167
Price: 675 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS044167

Background: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or test applications! This kit is intended to be used to determine the level of BMP15 (hereafter termed "analyte") in undiluted… More details

$675 / 48-Strip-Wells +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Bone Morphogenetic Protein 15 (BMP15), ELISA Kit

Full Product Name

Mouse Bone Morphogenetic Protein 15 ELISA Kit

Product Gene Name

BMP15 elisa kit

Species Reactivity

Mouse

Assay Type

Quantitative Sandwich

Detection Range

62.5pg/ml-2000pg/ml

Sensitivity

10pg/ml

Preparation and Storage

Store all reagents at 2-8 degree C

Inter-assay Precision

Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

Intra-assay Precision

Intra-assay CV (%) is less than 15%.

Molecular Weight

45,055 Da

Chromosome Location

Chromosome: X; NC_000023.10 (50653735..50659641). Location: Xp11.2

OMIM

300247

3D Structure

ModBase 3D Structure for O95972

Other Notes

Small volumes of BMP15 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMP15 purchase

MBS044167 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 15 (BMP15) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing BMP15. The ELISA analytical biochemical technique of the MBS044167 kit is based on BMP15 antibody-BMP15 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect BMP15 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, BMP15. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for BMP15. It may not necessarily be applicable to this product.

NCBI GI #

257743454

NCBI GeneID

9210

NCBI Accession #

NP_005439.2

UniProt Primary Accession #

O95972

UniProt Secondary Accession #

Q17RM6; Q5JST1; Q9UMS1

UniProt Related Accession #

O95972

GenBank Nucleotide #

NM_005448.2

NCBI Official Full Name

bone morphogenetic protein 15

NCBI Official Synonym Full Names

bone morphogenetic protein 15

NCBI Official Symbol

BMP15

NCBI Official Synonym Symbols

ODG2; POF4; GDF9B

UniProt Protein Name

Bone morphogenetic protein 15

UniProt Synonym Protein Names

Growth/differentiation factor 9B

Protein Family

Bone morphogenetic protein

UniProt Gene Name

BMP15

UniProt Synonym Gene Names

GDF9B; BMP-15; GDF-9B

UniProt Entry Name

BMP15_HUMAN

NCBI Protein Information

bone morphogenetic protein 15; BMP-15; GDF-9B; growth/differentiation factor 9B

NCBI Summary for BMP15

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9. Defects in this gene are the cause of ovarian dysgenesis 2.[provided by RefSeq, Sep 2009]

UniProt Comments for BMP15

BMP15: May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. Defects in BMP15 are the cause of ovarian dysgenesis type 2 (ODG2); also known as X-linked hypergonadotropic ovarian dysgenesis or hypergonadotropic ovarian failure due to ovarian dysgenesis. Ovarian dysgenesis leads to ovarian failure and accounts for about half of the cases of primary amenorrhea. Defects in BMP15 are the cause of premature ovarian failure type 4 (POF4). An ovarian disorder defined as the cessation of ovarian function under the age of 40 years. It is characterized by oligomenorrhea or amenorrhea, in the presence of elevated levels of serum gonadotropins and low estradiol. Belongs to the TGF-beta family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: Xp11.2

Cellular Component: extracellular space; cytoplasm

Molecular Function: growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: regulation of apoptosis; BMP signaling pathway; granulosa cell development; ovarian follicle development; regulation of MAPKKK cascade; positive regulation of transcription, DNA-dependent; female gamete generation; cell development

Disease: Ovarian Dysgenesis 2

Research Articles on BMP15

1. BMP15 and GDF9 transcript levels increase in mature oocytes from women with polycystic ovary syndrome after ovarian stimulation, and might inhibit the progesterone secretion by follicular cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BMP15 elisa kit

Reference Product	PubMed Publications
GDF9 elisa kit	>292 publications with BMP15 and GDF9
BMPR2 elisa kit	>34 publications with BMP15 and BMPR2
BMPR1B elisa kit	>18 publications with BMP15 and BMPR1B
FSHR elisa kit	>13 publications with BMP15 and FSHR
NOBOX elisa kit	>5 publications with BMP15 and NOBOX
FIGLA elisa kit	>5 publications with BMP15 and FIGLA
FGF7 elisa kit	>2 publications with BMP15 and FGF7
DIAPH2 elisa kit	>1 publications with BMP15 and DIAPH2
POF1B elisa kit	>1 publications with BMP15 and POF1B

Pathways associated with BMP15 elisa kit

Products by Pathway	Pathway Diagram
Ovarian Steroidogenesis Pathway antibodies	Ovarian Steroidogenesis Pathway Diagram
Ovarian Steroidogenesis Pathway antibodies	Ovarian Steroidogenesis Pathway Diagram

Diseases associated with BMP15 elisa kit

Disease Name	Pubmed Publications
Infertility, Female Antibodies	>55 publications with BMP15 and Infertility, Female
Neoplasms Antibodies	>13 publications with BMP15 and Neoplasms
Polycystic Ovary Syndrome Antibodies	>12 publications with BMP15 and Polycystic Ovary Syndrome
Urogenital Abnormalities Antibodies	>8 publications with BMP15 and Urogenital Abnormalities
Necrosis Antibodies	>4 publications with BMP15 and Necrosis
Abnormalities, Drug-Induced Antibodies	>2 publications with BMP15 and Abnormalities, Drug-Induced
Weight Loss Antibodies	>2 publications with BMP15 and Weight Loss
Immune System Diseases Antibodies	>2 publications with BMP15 and Immune System Diseases
Hyperplasia Antibodies	>1 publications with BMP15 and Hyperplasia