Anti-ST2L Monoclonal Antibody – Cat# MBS442021

ST2L Antibody – Monoclonal

Name: ST2L Antibody; Monoclonal; MyBioSource
Brand: MyBioSource
SKU: MBS442021
Price: 860 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS442021

Human ST2L biotinylated monoclonal antibody (Clone B4E6) for the identification and purification of human type 2 lymphocyte (Th2) subsetsOverview: T1/ST2 (also known as IL-1 R4 or IL-33Ra) is a transmembrane glycoprotein expressed on mast cells and Th2 cells.… More details

$860 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ST2L, Monoclonal Antibody

Full Product Name

Monocloncal Antibody to human ST2L Biotinylated

Product Gene Name

anti-ST2L antibody

Product Synonym Names

ST2L Monoclonal Antibody, Biotinylated

Clonality

Monoclonal

Isotype

IgG1

Clone Number

B4E6

Form/Format

The biotinylated antibody is supplied in PBS and purified over protein G-sepharose from concentrated tissue culture supernatant. The antibody is supplied with 0.1% sodium azide as preservative.

Concentration

200ul (1mg/ml) (lot specific)

Specificity

This clone recognizes hST2L specifically on the cell surface of human type 2 (Th2, Tc2, NK2 and NKT2) but not type 1 lymphocytes.

Product Categories/Family for anti-ST2L antibody

Antibodies to T Cell

Applications Tested/Suitable for anti-ST2L antibody

Flow Cytometry (FC/FACS), Cell Sorting, Immunohistochemistry (IHC) with hybridoma culture supernatant

Other Notes

Small volumes of anti-ST2L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ST2L purchase

MBS442021 is an antibody targeting ST2L. Also known as Monocloncal Antibody to human ST2L Biotinylated.

Additional Details

NCBI/Uniprot data below describe general gene information for ST2L. It may not necessarily be applicable to this product.

NCBI GI #

72534639

NCBI Accession #

BAA82405.2

NCBI Official Full Name

ST2L

UniProt Comments for ST2L

IL1RL1: receptor for IL33. Its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of ERK1 and/or ERK2, p38-alpha, and JNK1. Apparently promotes the activation and differentiation of T-helper 2 cells. Belongs to the interleukin-1 receptor family. Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Three isoforms of the human protein are produced by alternative splicing. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.

Protein type: Receptor, cytokine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: extracellular matrix; integral to membrane; extracellular region; external side of plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; protein binding; receptor signaling protein activity; interleukin-1 receptor activity

Biological Process: negative regulation of T-helper 1 type immune response; negative regulation of interferon-gamma production; immune response; negative regulation of I-kappaB kinase/NF-kappaB cascade; signal transduction; positive regulation of interleukin-5 production; positive regulation of inflammatory response; positive regulation of macrophage activation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.