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RAB14 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS448016
SPECIAL PROMOTIONAL PRICING for a limited time

RAB14, member RAS oncogene familyRAB14 belongs to the large RAB family of low molecular weight GTPases that are involved in intracellular membrane trafficking. This protein is expressed at high levels in kidney, lung, brain, spleen and thymus and it is… More details

$405 / 0.4 mg +1 FREE 8GB USB
Product Documentation
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Rab14, Polyclonal Antibody
Full Product Name
Rab14 Polyclonal Antibody
Product Gene Name
anti-Rab14 antibody
Product Synonym Names
Anti-Rab14; F protein-binding protein 1; bA165P4.3 (member RAS oncogene family); ras-related protein Rab-14; small GTP binding protein Rab14 antibody)
Clonality
Polyclonal
Isotype
IgG
Host
Goat
Species Reactivity
Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian
Form/Format
Polyclonal antibody supplied as (2 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.
Specificity
Detects Rab14 by Western blot in transfected cells with GFP-Rab14.
Preparation and Storage
For continuous use, store at 2-8 deg;C for one-two days. For extended storage, store in -20 deg;C freezer. Working dilution samples should be discarded if not used within 12 hours.
Molecular Weight
23,897 Da
Chromosome Location
Chromosome: 9; NC_000009.12 (121178137..121202087, complement). Location: 9q32-q34.11
OMIM
612673
3D Structure
ModBase 3D Structure for P61106
Gene Identifier
ENSG00000119396
Immunogen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab14 produced in E. coli.
Antigen
Purified recombinant peptide derived from within residues 110 aa to the C-terminus of mouse Rab14 produced in E. coli.
Applications Tested/Suitable for anti-Rab14 antibody
Immunofluorescence (IF), Western Blot (WB)
Application Notes for anti-Rab14 antibody
Western Blot: 1:250-1:2,000

Reactivity Chart of anti-Rab14 antibody

Goat Anti-RAB14 Polyclonal Antibody – Cat# MBS448016

Testing Data of anti-Rab14 antibody

Goat Anti-RAB14 Polyclonal Antibody, Testing Data – Cat# MBS448016

Other Notes

Small volumes of anti-Rab14 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rab14 purchase

MBS448016 is an antibody targeting Rab14. Also known as Rab14 Polyclonal Antibody. Reactive in Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for Rab14. It may not necessarily be applicable to this product.

NCBI GI #
48146905
NCBI GeneID
51552
NCBI Accession #
CAG33675.1
UniProt Primary Accession #
P61106
UniProt Secondary Accession #
P35287; Q5JVD4; Q6Q7K5; Q969L0; Q9UI11; B3KR31
UniProt Related Accession #
P61106
NCBI Official Full Name
RAB14
NCBI Official Synonym Full Names
RAB14, member RAS oncogene family
NCBI Official Symbol
RAB14
NCBI Official Synonym Symbols
FBP; RAB-14
UniProt Protein Name
Ras-related protein Rab-14
Protein Family
Ras-related protein
UniProt Gene Name
RAB14
UniProt Entry Name
RAB14_HUMAN
NCBI Protein Information
ras-related protein Rab-14; F protein-binding protein 1; small GTP binding protein RAB14; bA165P4.3 (member RAS oncogene family)

NCBI Summary for Rab14

RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]).[supplied by OMIM, Mar 2009]
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UniProt Comments for Rab14

Function: Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes

By similarity. Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. Ref.17

Subunit structure: Interacts with KIF16B

By similarity. Interacts with ZFYVE20. Ref.18

Subcellular location: Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side

By similarity. Golgi apparatus › trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle › phagosome. Cytoplasmic vesicle › phagosome membrane; Lipid-anchor; Cytoplasmic side

By similarity. Note: Recruited to recycling endosomes by DENND6A. Recruited to phagosomes containing S.aureus or M.tuberculosis. Ref.13 Ref.16 Ref.17

Sequence similarities: Belongs to the small GTPase superfamily. Rab family.

Sequence caution: The sequence CAI12361.1 differs from that shown. Reason: Erroneous gene model prediction.
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Research Articles on Rab14

1. Rab5a, Rab8a and Rab14 are major regulators of MT1-MMP trafficking and invasive migration of primary human macrophages.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Rab14 antibody

 Reference Product  PubMed Publications
 RAB10 antibody  >15 publications with Rab14 and RAB10
 RAB8A antibody  >5 publications with Rab14 and RAB8A
 SLC2A4 antibody  >3 publications with Rab14 and SLC2A4
 TBC1D4 antibody  >2 publications with Rab14 and TBC1D4
 MYO5A antibody  >1 publications with Rab14 and MYO5A
 RAB13 antibody  >1 publications with Rab14 and RAB13

Pathways associated with anti-Rab14 antibody

 Products by Pathway  Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Translocation Of GLUT4 To The Plasma Membrane Pathway antibodies  Translocation Of GLUT4 To The Plasma Membrane Pathway Diagram

Diseases associated with anti-Rab14 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with Rab14 and Neoplasms
 Lung Neoplasms Antibodies  >2 publications with Rab14 and Lung Neoplasms
 Disease Models, Animal Antibodies  >1 publications with Rab14 and Disease Models, Animal

Organs/Tissues associated with anti-Rab14 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with Rab14 and Lung
 Blood Antibodies  >6 publications with Rab14 and Blood
 Brain Antibodies  >6 publications with Rab14 and Brain
 Muscle Antibodies  >5 publications with Rab14 and Muscle
 Nerve Antibodies  >3 publications with Rab14 and Nerve
 Kidney Antibodies  >3 publications with Rab14 and Kidney
 Liver Antibodies  >2 publications with Rab14 and Liver
 Embryonic Tissue Antibodies  >2 publications with Rab14 and Embryonic Tissue
 Vascular Antibodies  >2 publications with Rab14 and Vascular
 Intestine Antibodies  >1 publications with Rab14 and Intestine
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