Goat Anti-RAB8B Polyclonal Antibody – Cat# MBS448074

RAB8B Antibody – Goat Polyclonal

Name: RAB8B Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS448074
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS448074

Goat polyclonal antibody to mouse Rab8. Rab8 belongs to the small GTPase superfamily, Rab family. It has cell-type specific function during the process of exocytosis and coordinates regulation of the cytoskeleton. Rab8 also appears to interface with endocytic… More details

$405 / 0.6 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rab8b, Polyclonal Antibody

Full Product Name

Anti-Rab8b

Product Gene Name

anti-RAB8B antibody

Product Synonym Names

RAB8A; RAB8B; RAS-associated protein RAB8A; ras-related protein Rab-8B; ras-related protein Rab-8A; ras-related protein Rab-8B antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other

Form/Format

Polyclonal antibody supplied as a 200 ul (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Purity/Purification

Epitope Affinity Purified

Specificity

Detects Rab8b protein in transfected cells with GFP-Rab8b cds by Western blot. This Ab is specific for Rab8b. It does not recognize Rab8a.

Preparation and Storage

For continuous use, store at 2-8 degree C for one-two days. For extended storage, store in -20 degree C freezer. Working dilution samples should be discarded if not used within 12 hours.

Molecular Weight

23,584 Da

OMIM

613532

Handling

The antibody solution should be gently mixed before use.

Conjugation

Unconjugated

Antigen

Purified recombinant peptide derived from within residues 107 aa to the C-terminus of mouse Rab8b produced in E. coli.

Applications Tested/Suitable for anti-RAB8B antibody

Western Blot (WB)

Application Notes for anti-RAB8B antibody

Western Blot- 1:250-1:1,000

Other Notes

Small volumes of anti-RAB8B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB8B purchase

MBS448074 is an antibody targeting RAB8B. Also known as Anti-Rab8b. Reactive in Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB8B. It may not necessarily be applicable to this product.

NCBI GI #

119598048

NCBI GeneID

51762

NCBI Accession #

EAW77642.1

UniProt Secondary Accession #

Q5JPC4; Q9P293

UniProt Related Accession #

Q92930

NCBI Official Full Name

RAB8B, member RAS oncogene family, isoform CRA_b

NCBI Official Synonym Full Names

RAB8B, member RAS oncogene family

NCBI Official Symbol

RAB8B

UniProt Protein Name

Ras-related protein Rab-8B

Protein Family

Ras-related protein

UniProt Gene Name

RAB8B

UniProt Entry Name

RAB8B_HUMAN

NCBI Protein Information

ras-related protein Rab-8B; RAB-8b protein

NCBI Summary for RAB8B

RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes (summary by Chen et al., 1997 [PubMed 9030196]).[supplied by OMIM, Nov 2010]

UniProt Comments for RAB8B

RAB8B: May be involved in vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric; G protein; Motility/polarity/chemotaxis; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: peroxisomal membrane; trans-Golgi network transport vesicle; synaptic vesicle; phagocytic vesicle membrane; mitochondrion; perinuclear region of cytoplasm; secretory granule membrane; plasma membrane; phagocytic vesicle; endosome

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; TPR domain binding; receptor binding

Biological Process: metabolic process; positive regulation of cell projection organization and biogenesis; protein secretion; positive regulation of adrenocorticotropic hormone secretion; regulation of exocytosis; antigen processing and presentation; synaptic vesicle exocytosis; cellular response to insulin stimulus; Golgi vesicle fusion to target membrane; cilium biogenesis; Rab protein signal transduction; protein import into peroxisome membrane; vesicle docking during exocytosis

Research Articles on RAB8B

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB8B antibody

Reference Product	PubMed Publications
PEX5L antibody	>4 publications with RAB8B and PEX5L
RAB3IP antibody	>1 publications with RAB8B and RAB3IP
OTOF antibody	>1 publications with RAB8B and OTOF
MYO5B antibody	>1 publications with RAB8B and MYO5B

Diseases associated with anti-RAB8B antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>1 publications with RAB8B and Immune System Diseases
Memory Disorders Antibodies	>1 publications with RAB8B and Memory Disorders
Hearing Loss Antibodies	>1 publications with RAB8B and Hearing Loss
Learning Disorders Antibodies	>1 publications with RAB8B and Learning Disorders
Disease Models, Animal Antibodies	>1 publications with RAB8B and Disease Models, Animal
Atrophy Antibodies	>1 publications with RAB8B and Atrophy

Organs/Tissues associated with anti-RAB8B antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>24 publications with RAB8B and Brain
Nerve Antibodies	>8 publications with RAB8B and Nerve
Kidney Antibodies	>4 publications with RAB8B and Kidney
Embryonic Tissue Antibodies	>3 publications with RAB8B and Embryonic Tissue
Spleen Antibodies	>2 publications with RAB8B and Spleen
Muscle Antibodies	>2 publications with RAB8B and Muscle
Eye Antibodies	>2 publications with RAB8B and Eye
Ear Antibodies	>2 publications with RAB8B and Ear
Testis Antibodies	>2 publications with RAB8B and Testis
Intestine Antibodies	>1 publications with RAB8B and Intestine