Goat Anti-RAB11B Polyclonal Antibody – Cat# MBS448075

RAB11B Antibody – Goat Polyclonal

Name: RAB11B Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS448075
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS448075

Goat polyclonal antibody to mouse Rab11b. Rab11 belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and plays essential roles in vesicle and granule targeting. Similar to Rab11a, it has been shown that Rab11b associates with… More details

$405 / 0.6 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rab11b, Polyclonal Antibody

Full Product Name

Anti-Rab11b

Product Gene Name

anti-RAB11B antibody

Product Synonym Names

GTP-binding protein YPT3; member of RAS oncogene family; ras-related protein Rab-11B antibody

Clonality

Polyclonal

Isotype

IgG

Host

Goat

Species Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other

Form/Format

Polyclonal antibody supplied as a 200 ul (3 mg/ml) aliquot in PBS, 20% glycerol and 0.05% sodium azide. This antibody is epitope-affinity purified from goat antiserum.

Purity/Purification

Epitope Affinity Purified

Specificity

Detects a band of 25 kDa by Western blot in the following human, rat and mouse whole cell lysates and transfected cells with GFP-Rab11b cds. This Ab is specific for Rab11b, it does not recognize Rab11a

Preparation and Storage

For continuous use, store at 2-8 degree C for one-two days. For extended storage, store in -20 degree C freezer. Working dilution samples should be discarded if not used within 12 hours.

Molecular Weight

19,971 Da

OMIM

604198

3D Structure

ModBase 3D Structure for Q6FHR0

Handling

The antibody solution should be gently mixed before use.

Conjugation

Unconjugated

Antigen

Purified recombinant peptide derived from within residues 120 aa to the C-terminus of mouse Rab11b produced in E. coli.

Applications Tested/Suitable for anti-RAB11B antibody

Western Blot (WB)

Application Notes for anti-RAB11B antibody

Western Blot- 1:250-1:2,000

Other Notes

Small volumes of anti-RAB11B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RAB11B purchase

MBS448075 is an antibody targeting RAB11B. Also known as Anti-Rab11b. Reactive in Human, Mouse, Rat, Bovine, Canine, Chicken, Avian, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep, Simian, Other. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB11B. It may not necessarily be applicable to this product.

NCBI GI #

49456343

NCBI GeneID

9230

NCBI Accession #

CAG46492.1

UniProt Primary Accession #

Q6FHR0

UniProt Secondary Accession #

Q2YDT2; Q5U0I1; Q6FHR0; Q6FI42; Q8NI07; A5YM50; B2R7I4; B4DMK0; D6W671

UniProt Related Accession #

Q15907

NCBI Official Full Name

RAB11B, partial

NCBI Official Synonym Full Names

RAB11B, member RAS oncogene family

NCBI Official Symbol

RAB11B

NCBI Official Synonym Symbols

H-YPT3

UniProt Protein Name

Ras-related protein Rab-11B

UniProt Synonym Protein Names

GTP-binding protein YPT3

Protein Family

Ras-related protein

UniProt Gene Name

RAB11B

UniProt Synonym Gene Names

YPT3

UniProt Entry Name

RB11B_HUMAN

NCBI Protein Information

ras-related protein Rab-11B; GTP-binding protein YPT3; RAB11B, member of RAS oncogene family

NCBI Summary for RAB11B

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

UniProt Comments for RAB11B

RAB11B: GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: synaptic vesicle; phagocytic vesicle membrane; recycling endosome; synaptic vesicle membrane; mitochondrion; recycling endosome membrane; phagocytic vesicle; cell junction

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding

Biological Process: receptor recycling; intracellular protein transport; regulated secretory pathway; constitutive secretory pathway; transferrin transport; Rab protein signal transduction; melanosome transport

Research Articles on RAB11B

1. we determined a crystal structure of the PKG II LZ-Rab11b complex. The PKG II LZ domain presents a mostly nonpolar surface onto which Rab11b docks, through van der Waals interactions

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB11B antibody

Reference Product	PubMed Publications
RAB11A antibody	>23 publications with RAB11B and RAB11A
RAB8A antibody	>3 publications with RAB11B and RAB8A
RAB7A antibody	>1 publications with RAB11B and RAB7A
RAB1A antibody	>1 publications with RAB11B and RAB1A
RAB1B antibody	>1 publications with RAB11B and RAB1B

Pathways associated with anti-RAB11B antibody

Products by Pathway	Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Vasopressin-regulated Water Reabsorption Pathway antibodies	Vasopressin-regulated Water Reabsorption Pathway Diagram
Vasopressin-regulated Water Reabsorption Pathway antibodies	Vasopressin-regulated Water Reabsorption Pathway Diagram

Diseases associated with anti-RAB11B antibody

Disease Name	Pubmed Publications
Brain Diseases Antibodies	>2 publications with RAB11B and Brain Diseases
Liver Diseases Antibodies	>2 publications with RAB11B and Liver Diseases
Fibrosis Antibodies	>2 publications with RAB11B and Fibrosis
Congenital Abnormalities Antibodies	>1 publications with RAB11B and Congenital Abnormalities
Heart Diseases Antibodies	>1 publications with RAB11B and Heart Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with RAB11B and Carcinoma, Hepatocellular
Heart Defects, Congenital Antibodies	>1 publications with RAB11B and Heart Defects, Congenital
Kidney Diseases Antibodies	>1 publications with RAB11B and Kidney Diseases
Liver Neoplasms Antibodies	>1 publications with RAB11B and Liver Neoplasms

Organs/Tissues associated with anti-RAB11B antibody

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>8 publications with RAB11B and Kidney
Heart Antibodies	>5 publications with RAB11B and Heart
Stomach Antibodies	>3 publications with RAB11B and Stomach
Brain Antibodies	>3 publications with RAB11B and Brain
Liver Antibodies	>2 publications with RAB11B and Liver
Bone Antibodies	>2 publications with RAB11B and Bone
Salivary Gland Antibodies	>2 publications with RAB11B and Salivary Gland
Muscle Antibodies	>2 publications with RAB11B and Muscle
Intestine Antibodies	>1 publications with RAB11B and Intestine
Pancreas Antibodies	>1 publications with RAB11B and Pancreas