Haptoglobin (HPT) ELISA Kit for Mouse

Name: Mouse HPT ELISA Kit; Haptoglobin; MyBioSource
Brand: MyBioSource
SKU: MBS450409
Price: 485 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS450409

MBS450409 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Haptoglobin (Hpt) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$485 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Haptoglobin (Hpt), ELISA Kit

Full Product Name

Mouse Haptoglobin (Hpt) ELISA Kit

Product Gene Name

Hpt elisa kit

Product Synonym Names

HP; Hp2-Alpha; Alpha-2-Macroglobulin; Zonulin

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, plasma and other biological fluids.

Detection Range

31.25-2000ng/mL

Sensitivity

13.9ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

38,752 Da

3D Structure

ModBase 3D Structure for Q61646

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of Hpt elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Hpt. It may not necessarily be applicable to this product.

NCBI GI #

8850219

NCBI GeneID

15439

NCBI Accession #

NP_059066.1

UniProt Primary Accession #

Q61646

UniProt Related Accession #

Q61646

GenBank Nucleotide #

NM_017370.2

NCBI Official Full Name

haptoglobin isoform 1 preproprotein

NCBI Official Synonym Full Names

haptoglobin

NCBI Official Symbol

NCBI Official Synonym Symbols

HP-1; preHP2

UniProt Protein Name

Haptoglobin

UniProt Synonym Protein Names

Zonulin

Protein Family

Hypoxanthine/guanine phosphoribosyltransferase

UniProt Gene Name

NCBI Protein Information

haptoglobin

NCBI Summary for Hpt

This gene encodes a plasma glycoprotein called haptoglobin that binds free hemoglobin. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta subunits that form a disulfide-linked tetrameric protein that plays an important role in the sequestration and clearance of extracorpuscular hemoglobin. Mice lacking the encoded protein exhibit stunted development of lymphoid organs associated with lower counts of mature T and B cells in the blood and secondary lymphoid compartments. [provided by RefSeq, Aug 2016]

UniProt Comments for Hpt

As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway ().

Research Articles on Hpt

1. the interaction between haptoglobin genotype and vitamin E affects atherosclerotic plaque progression and stability

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with Hpt elisa kit

Reference Product	PubMed Publications
Cd163 elisa kit	>75 publications with Hpt and Cd163
Apoa1 elisa kit	>17 publications with Hpt and Apoa1

Pathways associated with Hpt elisa kit

Products by Pathway	Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
Scavenging Of Heme From Plasma Pathway antibodies	Scavenging Of Heme From Plasma Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram

Diseases associated with Hpt elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>2049 publications with Hpt and Cardiovascular Diseases
Inflammation Antibodies	>1458 publications with Hpt and Inflammation
Hypersensitivity Antibodies	>748 publications with Hpt and Hypersensitivity
Disease Models, Animal Antibodies	>654 publications with Hpt and Disease Models, Animal
Hypertension Antibodies	>646 publications with Hpt and Hypertension
Autoimmune Diseases Antibodies	>620 publications with Hpt and Autoimmune Diseases
Kidney Diseases Antibodies	>576 publications with Hpt and Kidney Diseases
Necrosis Antibodies	>561 publications with Hpt and Necrosis
Fibrosis Antibodies	>552 publications with Hpt and Fibrosis
Arthritis Antibodies	>423 publications with Hpt and Arthritis

Organs/Tissues associated with Hpt elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>6516 publications with Hpt and Blood
Liver Antibodies	>1521 publications with Hpt and Liver
Lung Antibodies	>1400 publications with Hpt and Lung
Bone Antibodies	>1031 publications with Hpt and Bone
Muscle Antibodies	>890 publications with Hpt and Muscle
Kidney Antibodies	>850 publications with Hpt and Kidney
Skin Antibodies	>692 publications with Hpt and Skin
Intestine Antibodies	>551 publications with Hpt and Intestine
Joint Antibodies	>426 publications with Hpt and Joint
Connective Tissue Antibodies	>403 publications with Hpt and Connective Tissue