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DGK Epsilon (DGKepsilon) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4505682

MBS4505682 is an antibody targeting DGKepsilon. Also known as Rabbit anti-DGK epsilon Antibody. Reactive in Human, Monkey. Host: Rabbit. More details

$250 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DGK epsilon (DGKepsilon), Polyclonal Antibody
Full Product Name
Rabbit anti-DGK epsilon Antibody
Product Gene Name
anti-DGKepsilon antibody
Product Synonym Names
DAGK5; Diacylglycerol kinase epsilon; DAG kinase epsilon; Diglyceride kinase epsilon; DGK-epsilon
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
63,927 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (54911460..54946036). Location: 17q22
OMIM
601440
3D Structure
ModBase 3D Structure for P52429
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DGK epsilon. The exact sequence is proprietary.

Product Categories/Family for anti-DGKepsilon antibody

Primary antibodies
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-DGKepsilon antibody
Western Blot (WB)
Application Notes for anti-DGKepsilon antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-DGKepsilon antibody

Western blot analysis of DGK epsilon expression in HeLa (A), HEK293T (B) whole cell lysates.
Rabbit Anti-DGKepsilon Polyclonal Antibody – Cat# MBS4505682

Other Notes

Small volumes of anti-DGKepsilon antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DGKepsilon. It may not necessarily be applicable to this product.

NCBI GI #
4503313
NCBI GeneID
8526
NCBI Accession #
NP_003638.1
UniProt Primary Accession #
P52429
UniProt Secondary Accession #
Q9R1C6
UniProt Related Accession #
P52429
GenBank Nucleotide #
NM_003647.2
NCBI Official Full Name
diacylglycerol kinase epsilon
NCBI Official Synonym Full Names
diacylglycerol kinase, epsilon 64kDa
NCBI Official Symbol
DGKE
NCBI Official Synonym Symbols
DGK; DAGK5; DAGK6; NPHS7
UniProt Protein Name
Diacylglycerol kinase epsilon
UniProt Synonym Protein Names
Diglyceride kinase epsilon
Protein Family
Diacylglycerol kinase
UniProt Gene Name
DGKE
UniProt Synonym Gene Names
DAGK5; DAG kinase epsilon; DGK-epsilon
UniProt Entry Name
DGKE_HUMAN
NCBI Protein Information
diacylglycerol kinase epsilon; DGK-epsilon; DAG kinase epsilon; diglyceride kinase epsilon

NCBI Summary for DGKepsilon

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis. [provided by RefSeq, Jul 2008]
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UniProt Comments for DGKepsilon

DGKE: Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition. Belongs to the eukaryotic diacylglycerol kinase family.

Protein type: Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Membrane protein, integral; EC 2.7.1.107; Motility/polarity/chemotaxis; Kinase, lipid

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: membrane; cytoplasm; integral to membrane; plasma membrane

Molecular Function: metal ion binding; diacylglycerol kinase activity; ATP binding; NAD+ kinase activity

Biological Process: platelet activation; protein kinase C activation; blood coagulation; phosphorylation; phospholipid biosynthetic process

Disease: Nephrotic Syndrome, Type 7
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Research Articles on DGKepsilon

1. Substrate specificity of DGKE is not a consequence of competition with hydrolysis of ATP.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DGKepsilon antibody

 Products by Pathway  Pathway Diagram
 Effects Of PIP2 Hydrolysis Pathway antibodies  Effects Of PIP2 Hydrolysis Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Glycerophospholipid Metabolism Pathway antibodies  Glycerophospholipid Metabolism Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Phosphatidylinositol Signaling System Pathway antibodies  Phosphatidylinositol Signaling System Pathway Diagram

Diseases associated with anti-DGKepsilon antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >3 publications with DGKepsilon and Kidney Diseases
 Atypical hemolytic uremic syndrome Antibodies  >3 publications with DGKepsilon and Atypical hemolytic uremic syndrome
 Hematologic Diseases Antibodies  >2 publications with DGKepsilon and Hematologic Diseases
 Seizures Antibodies  >1 publications with DGKepsilon and Seizures
 Depressive Disorder Antibodies  >1 publications with DGKepsilon and Depressive Disorder

Organs/Tissues associated with anti-DGKepsilon antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >2 publications with DGKepsilon and Kidney
 Liver Antibodies  >1 publications with DGKepsilon and Liver
 Vascular Antibodies  >1 publications with DGKepsilon and Vascular
 Brain Antibodies  >1 publications with DGKepsilon and Brain
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