Coagulation Factor XII (F12) ELISA Kit for Mouse

Name: Mouse F12 ELISA Kit; Coagulation Factor XII; MyBioSource
Brand: MyBioSource
SKU: MBS450660
Price: 485 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS450660

MBS450660 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Coagulation Factor XII (F12) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$485 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Coagulation Factor XII (F12), ELISA Kit

Full Product Name

Mouse Coagulation Factor XII (F12) ELISA Kit

Product Gene Name

F12 elisa kit

Product Synonym Names

FXII; HAF; Contact Factor; Hageman Factor

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Plasma.

Detection Range

0.625-40ng/mL

Sensitivity

0.251ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

65,701 Da

3D Structure

ModBase 3D Structure for Q80YC5

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of F12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for F12. It may not necessarily be applicable to this product.

NCBI GI #

171906584

NCBI GeneID

58992

NCBI Accession #

NP_067464.2

UniProt Primary Accession #

Q80YC5

UniProt Secondary Accession #

O35727; Q6PER0

UniProt Related Accession #

Q80YC5

GenBank Nucleotide #

NM_021489.3

NCBI Official Full Name

coagulation factor XII preproprotein

NCBI Official Synonym Full Names

coagulation factor XII (Hageman factor)

NCBI Official Symbol

F12

NCBI Official Synonym Symbols

HAF; FXII

UniProt Protein Name

Coagulation factor XII

UniProt Synonym Protein Names

Hageman factor; HAF

Protein Family

Coagulation factor

UniProt Gene Name

F12

UniProt Synonym Gene Names

HAF

NCBI Protein Information

coagulation factor XII

NCBI Summary for F12

This gene encodes a glycoprotein coagulation factor that plays an important role in the intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that is autoactivated upon contact with negatively charged surfaces or misfolded protein aggregates. Mice lacking the encoded protein have a severe defect in forming stable fibrin clots. [provided by RefSeq, Apr 2015]

UniProt Comments for F12

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa ().

Research Articles on F12

1. Wild type mice developed carotid artery occlusion when the vessel was exposed to a 3.5% solution of ferric chloride (FeCl3). FXII-deficient mice were resistant to occlusion at 5% FeCl3 and partially resistant at 10% FeCl3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with F12 elisa kit

Reference Product	PubMed Publications
F11 elisa kit	>38 publications with F12 and F11
Serping1 elisa kit	>12 publications with F12 and Serping1
Klkb1 elisa kit	>7 publications with F12 and Klkb1
Gp1ba elisa kit	>5 publications with F12 and Gp1ba
Kng1 elisa kit	>5 publications with F12 and Kng1

Pathways associated with F12 elisa kit

Products by Pathway	Pathway Diagram
Blood Clotting Cascade Pathway antibodies	Blood Clotting Cascade Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Complement And Coagulation Cascades Pathway antibodies	Complement And Coagulation Cascades Pathway Diagram
Formation Of Fibrin Clot (Clotting Cascade) Pathway antibodies	Formation Of Fibrin Clot (Clotting Cascade) Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Intrinsic Pathway Of Fibrin Clot Formation antibodies	Intrinsic Pathway Of Fibrin Clot Formation Diagram

Diseases associated with F12 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>84 publications with F12 and Cardiovascular Diseases
Nervous System Diseases Antibodies	>61 publications with F12 and Nervous System Diseases
Carcinoma Antibodies	>60 publications with F12 and Carcinoma
Necrosis Antibodies	>33 publications with F12 and Necrosis
Neoplasms, Experimental Antibodies	>28 publications with F12 and Neoplasms, Experimental
Factor XII Deficiency Antibodies	>23 publications with F12 and Factor XII Deficiency
Angioedemas, Hereditary Antibodies	>22 publications with F12 and Angioedemas, Hereditary
Cell Transformation, Neoplastic Antibodies	>21 publications with F12 and Cell Transformation, Neoplastic
Fibrosis Antibodies	>20 publications with F12 and Fibrosis
Inflammation Antibodies	>19 publications with F12 and Inflammation

Organs/Tissues associated with F12 elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>94 publications with F12 and Embryonic Tissue
Liver Antibodies	>71 publications with F12 and Liver