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PPP3R1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4511367

MBS4511367 is an antibody targeting PPP3R1. Also known as Rabbit anti-PPP3R1 Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$270 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PPP3R1, Polyclonal Antibody
Full Product Name
Rabbit anti-PPP3R1 Antibody
Product Gene Name
anti-PPP3R1 antibody
Product Synonym Names
CNA2; CNB; Calcineurin subunit B type 1; Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Concentration
1mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid repeated freeze/thaw cycles.
Molecular Weight
170
OMIM
601302
3D Structure
ModBase 3D Structure for P63098
Immunogen
Recombinant full length protein of human PPP3R1

Product Categories/Family for anti-PPP3R1 antibody

Primary antibodies
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Applications Tested/Suitable for anti-PPP3R1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Application Notes for anti-PPP3R1 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
IP: 1:50-1:100

Western Blot (WB) of anti-PPP3R1 antibody

Western blot analysis of PPP3R1 expression in SW480 (A), MCF7 (B), mouse brain (C), rat testis (D) whole cell lysates.
Rabbit Anti-PPP3R1 Polyclonal Antibody – Cat# MBS4511367

Other Notes

Small volumes of anti-PPP3R1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PPP3R1. It may not necessarily be applicable to this product.

NCBI GI #
52000904
NCBI GeneID
5534
NCBI Accession #
P63098.2
UniProt Primary Accession #
P63098
UniProt Secondary Accession #
Q63810; P63100
UniProt Related Accession #
P63098
NCBI Official Full Name
Calcineurin subunit B type 1
NCBI Official Synonym Full Names
protein phosphatase 3, regulatory subunit B, alpha
NCBI Official Symbol
PPP3R1
NCBI Official Synonym Symbols
CNB; CNB1; CALNB1
UniProt Protein Name
Calcineurin subunit B type 1
UniProt Synonym Protein Names
Protein phosphatase 2B regulatory subunit 1; Protein phosphatase 3 regulatory subunit B alpha isoform 1
Protein Family
Calcineurin
UniProt Gene Name
PPP3R1
UniProt Synonym Gene Names
CNA2; CNB
UniProt Entry Name
CANB1_HUMAN
NCBI Protein Information
calcineurin subunit B type 1; calcineurin B, type I (19kDa); protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 (f

UniProt Comments for PPP3R1

PPP3R1: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Belongs to the calcineurin regulatory subunit family.

Protein type: Protein phosphatase, regulatory subunit; Cell development/differentiation; Apoptosis; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: nucleoplasm; cytosol; calcineurin complex; sarcolemma

Molecular Function: calmodulin binding; protein domain specific binding; protein binding; calcium-dependent protein serine/threonine phosphatase activity; calcium ion binding

Biological Process: calcineurin-NFAT signaling pathway; positive regulation of NFAT protein import into nucleus; dephosphorylation; apoptosis; innate immune response; positive regulation of transcription from RNA polymerase II promoter
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Research Articles on PPP3R1

1. Further evidence that specific variations in MAPT (rs3785883) and PPP3R1 (rs1868402) are associated with accelerated progression of Alzheimer's disease

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPP3R1 antibody

 Reference Product  PubMed Publications
 PPP3CB antibody  >7 publications with PPP3R1 and PPP3CB
 PPP3CA antibody  >7 publications with PPP3R1 and PPP3CA
 PPP3CC antibody  >3 publications with PPP3R1 and PPP3CC
 NFATC4 antibody  >2 publications with PPP3R1 and NFATC4
 NFATC1 antibody  >2 publications with PPP3R1 and NFATC1

Pathways associated with anti-PPP3R1 antibody

 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram

Diseases associated with anti-PPP3R1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with PPP3R1 and Nervous System Diseases
 Brain Diseases Antibodies  >4 publications with PPP3R1 and Brain Diseases
 Hypertrophy Antibodies  >3 publications with PPP3R1 and Hypertrophy
 Disease Models, Animal Antibodies  >2 publications with PPP3R1 and Disease Models, Animal
 Hypertrophy, Left Ventricular Antibodies  >2 publications with PPP3R1 and Hypertrophy, Left Ventricular
 Myocardial Ischemia Antibodies  >2 publications with PPP3R1 and Myocardial Ischemia
 Hypertension Antibodies  >1 publications with PPP3R1 and Hypertension
 Brain Injuries Antibodies  >1 publications with PPP3R1 and Brain Injuries
 Inflammation Antibodies  >1 publications with PPP3R1 and Inflammation

Organs/Tissues associated with anti-PPP3R1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with PPP3R1 and Muscle
 Brain Antibodies  >5 publications with PPP3R1 and Brain
 Nerve Antibodies  >2 publications with PPP3R1 and Nerve
 Bone Antibodies  >1 publications with PPP3R1 and Bone
 Liver Antibodies  >1 publications with PPP3R1 and Liver
 Spleen Antibodies  >1 publications with PPP3R1 and Spleen
 Pancreas Antibodies  >1 publications with PPP3R1 and Pancreas
 Embryonic Tissue Antibodies  >1 publications with PPP3R1 and Embryonic Tissue
 Placenta Antibodies  >1 publications with PPP3R1 and Placenta
 Lung Antibodies  >1 publications with PPP3R1 and Lung
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