Fc Fragment of IgA Receptor (FcaR) ELISA Kit for Human

Name: Human FcaR ELISA Kit; Fc Fragment of IgA Receptor; MyBioSource
Brand: MyBioSource
SKU: MBS451507
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451507

MBS451507 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fc Fragment Of IgA Receptor (FcaR) ELISA Kit target analytes in biological samples. The concentration gradients of the… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Fc Fragment Of IgA Receptor (FcaR), ELISA Kit

Full Product Name

Human Fc Fragment Of IgA Receptor (FcaR) ELISA Kit

Product Gene Name

FcaR elisa kit

Product Synonym Names

CD89 FcaRI Receptor I For The Fc Region Of Immunoglobulin A IgA Fc receptor Immunoglobulin alpha Fc receptor

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

0.781-50ng/mL

Sensitivity

0.35ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

28,343 Da

OMIM

X54150 mRNA

3D Structure

ModBase 3D Structure for P24071

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of FcaR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FcaR. It may not necessarily be applicable to this product.

NCBI GI #

4503673

NCBI GeneID

2204

NCBI Accession #

NP_001991.1

UniProt Primary Accession #

P24071

UniProt Secondary Accession #

Q13603; Q13604; Q15727; Q15728; Q1AJL7; Q1AJL8; Q1AJL9; Q53X38; Q53X39; Q92587; Q92588

UniProt Related Accession #

P24071

GenBank Nucleotide #

NM_002000.3

NCBI Official Full Name

immunoglobulin alpha Fc receptor isoform a

NCBI Official Synonym Full Names

Fc fragment of IgA receptor

NCBI Official Symbol

FCAR

NCBI Official Synonym Symbols

CD89; FcalphaRI; CTB-61M7.2

UniProt Protein Name

Immunoglobulin alpha Fc receptor

UniProt Synonym Protein Names

CD_antigen: CD89

Protein Family

Immunoglobulin alpha Fc receptor

UniProt Gene Name

FCAR

UniProt Synonym Gene Names

CD89; IgA Fc receptor

NCBI Protein Information

immunoglobulin alpha Fc receptor

NCBI Summary for FcaR

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for FcaR

Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.

Research Articles on FcaR

1. Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FcaR elisa kit

Products by Pathway	Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Phagosome Pathway antibodies	Phagosome Pathway Diagram
Staphylococcus Aureus Infection Pathway antibodies	Staphylococcus Aureus Infection Pathway Diagram
Staphylococcus Aureus Infection Pathway antibodies	Staphylococcus Aureus Infection Pathway Diagram

Diseases associated with FcaR elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>4 publications with FcaR and Inflammation
Kidney Diseases Antibodies	>3 publications with FcaR and Kidney Diseases
Heart Diseases Antibodies	>1 publications with FcaR and Heart Diseases
Nervous System Diseases Antibodies	>1 publications with FcaR and Nervous System Diseases
Liver Diseases Antibodies	>1 publications with FcaR and Liver Diseases
Weight Gain Antibodies	>1 publications with FcaR and Weight Gain
Carcinoma Antibodies	>1 publications with FcaR and Carcinoma
Chromosome Aberrations Antibodies	>1 publications with FcaR and Chromosome Aberrations
Necrosis Antibodies	>1 publications with FcaR and Necrosis

Organs/Tissues associated with FcaR elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>13 publications with FcaR and Blood