Myomesin 2 (MYOM2) ELISA Kit for Human

Name: Human MYOM2 ELISA Kit; Myomesin 2; MyBioSource
Brand: MyBioSource
SKU: MBS451535
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451535

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to MYOM2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Myomesin 2 (MYOM2), ELISA Kit

Full Product Name

Human Myomesin 2 (MYOM2) ELISA Kit

Product Gene Name

MYOM2 elisa kit

Product Synonym Names

TTNAP; Myomesin family member 2; 165 kDa titin-associated protein; 165 kDa connectin-associated protein

Species Reactivity

Human

Assay Type

Quantitative Sandwich

Samples

Human tissue homogenates or other biological fluids

Detection Range

0.312-20ng/mL

Sensitivity

< 0.123ng/mL

Specificity

This assay has high sensitivity and excellent specificity for detection of MYOM2. No significant cross-reactivity or interference between MYOM2 and analogues was observed.

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Inter-assay Precision

Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level MYOM2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%

Intra-assay Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level MYOM2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%

Molecular Weight

164,896 Da

OMIM

X69089 mRNA

3D Structure

ModBase 3D Structure for P54296

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of MYOM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MYOM2 purchase

MBS451535 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Myomesin 2 (MYOM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MYOM2. The ELISA analytical biochemical technique of the MBS451535 kit is based on MYOM2 antibody-MYOM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MYOM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MYOM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MYOM2. It may not necessarily be applicable to this product.

NCBI GI #

611434985

NCBI GeneID

9172

NCBI Accession #

NP_003961.3

UniProt Primary Accession #

P54296

UniProt Secondary Accession #

Q7Z3Y2

UniProt Related Accession #

P54296

GenBank Nucleotide #

NM_003970.3

NCBI Official Full Name

myomesin-2

NCBI Official Synonym Full Names

myomesin 2

NCBI Official Symbol

MYOM2

NCBI Official Synonym Symbols

TTNAP

UniProt Protein Name

Myomesin-2

UniProt Synonym Protein Names

165 kDa connectin-associated protein; 165 kDa titin-associated protein; M-protein; Myomesin family member 2

Protein Family

Myomesin

UniProt Gene Name

MYOM2

NCBI Protein Information

myomesin-2

NCBI Summary for MYOM2

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]

UniProt Comments for MYOM2

Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Research Articles on MYOM2

1. a direct interaction of dysferlin with Trim72/MG53, AHNAK, cytoplasmic dynein, myomesin-2 and calsequestrin-1, but not with caveolin-3 or dystrophin, is reported.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with MYOM2 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>3 publications with MYOM2 and Cardiovascular Diseases
Heart Diseases Antibodies	>3 publications with MYOM2 and Heart Diseases
Vascular Diseases Antibodies	>1 publications with MYOM2 and Vascular Diseases
Myocardial Infarction Antibodies	>1 publications with MYOM2 and Myocardial Infarction
Breast Neoplasms Antibodies	>1 publications with MYOM2 and Breast Neoplasms
Skin Diseases Antibodies	>1 publications with MYOM2 and Skin Diseases
Arrhythmias, Cardiac Antibodies	>1 publications with MYOM2 and Arrhythmias, Cardiac
Hypertrophy Antibodies	>1 publications with MYOM2 and Hypertrophy
Inflammation Antibodies	>1 publications with MYOM2 and Inflammation

Organs/Tissues associated with MYOM2 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>8 publications with MYOM2 and Muscle
Embryonic Tissue Antibodies	>2 publications with MYOM2 and Embryonic Tissue
Heart Antibodies	>2 publications with MYOM2 and Heart
Eye Antibodies	>1 publications with MYOM2 and Eye
Blood Antibodies	>1 publications with MYOM2 and Blood
Kidney Antibodies	>1 publications with MYOM2 and Kidney
Testis Antibodies	>1 publications with MYOM2 and Testis