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Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451641

MBS451641 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) ELISA Kit target analytes in biological samples. The… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12), ELISA Kit
Full Product Name
Human Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) ELISA Kit
Product Gene Name
P2RY12 elisa kit
Product Synonym Names
ADPG-R; HORK3; P2T(AC); P2Y(AC); P2Y(ADP); P2Y(cyc); P2Y12; SP1999; ADP-glucose receptor; P2Y12 platelet ADP receptor
Species Reactivity
Human
Assay Type
Sandwich
Samples
Tissue homogenates, cell lysates and other biological fluids.
Detection Range
0.156-10ng/mL
Sensitivity
0.063ng/mL
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
Molecular Weight
39,439 Da
OMIM
AF313449 mRNA
3D Structure
ModBase 3D Structure for Q9H244
Intra Assay
CV<10%
Inter Assay
CV<12%
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of P2RY12 elisa kit

Human P2RY12 ELISA Kit – Cat# MBS451641

Other Notes

Small volumes of P2RY12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for P2RY12. It may not necessarily be applicable to this product.

NCBI GI #
12232483
NCBI GeneID
64805
NCBI Accession #
NP_073625.1
UniProt Primary Accession #
Q9H244
UniProt Secondary Accession #
Q546J7; D3DNJ5
UniProt Related Accession #
Q9H244
GenBank Nucleotide #
NM_022788.4
NCBI Official Full Name
P2Y purinoceptor 12
NCBI Official Synonym Full Names
purinergic receptor P2Y12
NCBI Official Symbol
P2RY12
NCBI Official Synonym Symbols
HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
UniProt Protein Name
P2Y purinoceptor 12
UniProt Synonym Protein Names
ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor; P2Y(ADP); SP1999
Protein Family
P2Y purinoceptor
UniProt Gene Name
P2RY12
UniProt Synonym Gene Names
HORK3; P2Y12; ADPG-R; P2Y(ADP)
NCBI Protein Information
P2Y purinoceptor 12

NCBI Summary for P2RY12

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
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UniProt Comments for P2RY12

Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.

Research Articles on P2RY12

1. P2Y12 inhibitor monotherapy and dual antiplatelet therapy inhibit hemostatic system activation to a comparable extent in healthy volunteers.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with P2RY12 elisa kit

 Reference Product  PubMed Publications
 ADRA2A elisa kit  >9 publications with P2RY12 and ADRA2A
 ADORA1 elisa kit  >5 publications with P2RY12 and ADORA1
 PTGER3 elisa kit  >3 publications with P2RY12 and PTGER3
 GAL elisa kit  >1 publications with P2RY12 and GAL

Pathways associated with P2RY12 elisa kit

 Products by Pathway  Pathway Diagram
 ADP Signalling Through P2Y Purinoceptor 12 Pathway antibodies  ADP Signalling Through P2Y Purinoceptor 12 Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Nucleotide-like (purinergic) Receptors Pathway antibodies  Nucleotide-like (purinergic) Receptors Pathway Diagram
 P2Y Receptors Pathway antibodies  P2Y Receptors Pathway Diagram
 Platelet Activation Pathway antibodies  Platelet Activation Pathway Diagram

Diseases associated with P2RY12 elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >376 publications with P2RY12 and Cardiovascular Diseases
 Vascular Diseases Antibodies  >338 publications with P2RY12 and Vascular Diseases
 Heart Diseases Antibodies  >249 publications with P2RY12 and Heart Diseases
 Thrombosis Antibodies  >204 publications with P2RY12 and Thrombosis
 Coronary Artery Disease Antibodies  >112 publications with P2RY12 and Coronary Artery Disease
 Coronary Thrombosis Antibodies  >109 publications with P2RY12 and Coronary Thrombosis
 Myocardial Infarction Antibodies  >95 publications with P2RY12 and Myocardial Infarction
 Hemorrhage Antibodies  >82 publications with P2RY12 and Hemorrhage
 Atherosclerosis Antibodies  >35 publications with P2RY12 and Atherosclerosis
 Ischemia Antibodies  >35 publications with P2RY12 and Ischemia

Organs/Tissues associated with P2RY12 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >86 publications with P2RY12 and Heart
 Brain Antibodies  >49 publications with P2RY12 and Brain
 Muscle Antibodies  >18 publications with P2RY12 and Muscle
 Kidney Antibodies  >16 publications with P2RY12 and Kidney
 Ganglia Antibodies  >3 publications with P2RY12 and Ganglia
 Eye Antibodies  >3 publications with P2RY12 and Eye
 Connective Tissue Antibodies  >3 publications with P2RY12 and Connective Tissue
 Prostate Antibodies  >1 publications with P2RY12 and Prostate
 Bladder Antibodies  >1 publications with P2RY12 and Bladder
 Trachea Antibodies  >1 publications with P2RY12 and Trachea
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