Peptidase Inhibitor 3, Skin Derived (PI3) ELISA Kit for Human

Name: Human PI3 ELISA Kit; Peptidase Inhibitor 3, Skin Derived; MyBioSource
Brand: MyBioSource
SKU: MBS451831
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS451831

MBS451831 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Peptidase Inhibitor 3, Skin Derived (PI3) ELISA Kit target analytes in biological samples. The concentration gradients… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Peptidase Inhibitor 3, Skin Derived (PI3), ELISA Kit

Full Product Name

Human Peptidase Inhibitor 3, Skin Derived (PI3) ELISA Kit

Product Gene Name

PI3 elisa kit

Product Synonym Names

SKALP; ESI; WAP3; WFDC14; Elafin; Skin-Derived Antileukoproteinase; Cementoin; Elastase-specific inhibitor; WAP four-disulfide core domain protein 14

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, urine, saliva, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.132ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

12,270 Da

OMIM

Z18538 mRNA

3D Structure

ModBase 3D Structure for P19957

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of PI3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PI3. It may not necessarily be applicable to this product.

NCBI GI #

4505787

NCBI GeneID

5266

NCBI Accession #

NP_002629.1

UniProt Primary Accession #

P19957

UniProt Secondary Accession #

Q6FG74; E1P618

UniProt Related Accession #

P19957

GenBank Nucleotide #

NM_002638.3

NCBI Official Full Name

elafin preproprotein

NCBI Official Synonym Full Names

peptidase inhibitor 3

NCBI Official Symbol

PI3

NCBI Official Synonym Symbols

ESI; WAP3; SKALP; WFDC14; cementoin

UniProt Protein Name

Elafin

UniProt Synonym Protein Names

Elastase-specific inhibitor; ESI; Peptidase inhibitor 3; PI-3; Protease inhibitor WAP3; Skin-derived antileukoproteinase; SKALP; WAP four-disulfide core domain protein 14

Protein Family

Elafin

UniProt Gene Name

PI3

UniProt Synonym Gene Names

WAP3; WFDC14; ESI; PI-3; SKALP

NCBI Protein Information

elafin

NCBI Summary for PI3

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]

UniProt Comments for PI3

Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis.

Research Articles on PI3

1. Our study revealed that high elafin levels identified in smoking- and asthma-related microarray data sets and an epidemiologic study significantly reduced the risk of asthma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PI3 elisa kit

Reference Product	PubMed Publications
AKT1 elisa kit	>472 publications with PI3 and AKT1
PTEN elisa kit	>322 publications with PI3 and PTEN
CTNNB1 elisa kit	>88 publications with PI3 and CTNNB1

Pathways associated with PI3 elisa kit

Products by Pathway	Pathway Diagram
Antimicrobial Peptides Pathway antibodies	Antimicrobial Peptides Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Formation Of The Cornified Envelope Pathway antibodies	Formation Of The Cornified Envelope Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Keratinization Pathway antibodies	Keratinization Pathway Diagram

Diseases associated with PI3 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>423 publications with PI3 and Cardiovascular Diseases
Inflammation Antibodies	>323 publications with PI3 and Inflammation
Necrosis Antibodies	>300 publications with PI3 and Necrosis
Nervous System Diseases Antibodies	>273 publications with PI3 and Nervous System Diseases
Disease Models, Animal Antibodies	>234 publications with PI3 and Disease Models, Animal
Breast Neoplasms Antibodies	>231 publications with PI3 and Breast Neoplasms
Lung Diseases Antibodies	>146 publications with PI3 and Lung Diseases
Cell Transformation, Neoplastic Antibodies	>140 publications with PI3 and Cell Transformation, Neoplastic
Atherosclerosis Antibodies	>92 publications with PI3 and Atherosclerosis
Lung Neoplasms Antibodies	>91 publications with PI3 and Lung Neoplasms

Organs/Tissues associated with PI3 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1044 publications with PI3 and Blood
Muscle Antibodies	>730 publications with PI3 and Muscle
Brain Antibodies	>593 publications with PI3 and Brain
Lung Antibodies	>276 publications with PI3 and Lung
Prostate Antibodies	>126 publications with PI3 and Prostate
Skin Antibodies	>119 publications with PI3 and Skin
Intestine Antibodies	>96 publications with PI3 and Intestine
Ovary Antibodies	>69 publications with PI3 and Ovary
Adipose Tissue Antibodies	>67 publications with PI3 and Adipose Tissue
Thyroid Antibodies	>55 publications with PI3 and Thyroid