Fatty Acid Desaturase 2 (FADS2) ELISA Kit for Human

Name: Human FADS2 ELISA Kit; Fatty Acid Desaturase 2; MyBioSource
Brand: MyBioSource
SKU: MBS452309
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS452309

MBS452309 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Fatty Acid Desaturase 2 (FADS2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Fatty Acid Desaturase 2 (FADS2), ELISA Kit

Full Product Name

Human Fatty Acid Desaturase 2 (FADS2) ELISA Kit

Product Gene Name

FADS2 elisa kit

Product Synonym Names

LLCDL2; FADSD6; D6D; TU13; DES6; Delta-6-Desaturase; Delta(6) fatty acid desaturase

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

78.125-5000pg/mL

Sensitivity

28pg/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

48,883 Da

OMIM

AF126799 mRNA

3D Structure

ModBase 3D Structure for O95864

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of FADS2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FADS2. It may not necessarily be applicable to this product.

NCBI GI #

527498295

NCBI GeneID

9415

NCBI Accession #

NP_001268430.1

UniProt Primary Accession #

O95864

UniProt Secondary Accession #

Q6MZQ7; Q96H07; Q96SV8; Q9H3G3; Q9Y3X4; A8K2M6; B7Z634

UniProt Related Accession #

O95864

GenBank Nucleotide #

NM_001281501.1

NCBI Official Full Name

fatty acid desaturase 2 isoform 2

NCBI Official Synonym Full Names

fatty acid desaturase 2

NCBI Official Symbol

FADS2

NCBI Official Synonym Symbols

D6D; DES6; TU13; FADSD6; LLCDL2; SLL0262

UniProt Protein Name

Fatty acid desaturase 2

UniProt Synonym Protein Names

Acyl-CoA 6-desaturase; Delta(6) fatty acid desaturase; D6D; Delta(6) desaturase; Delta-6 desaturase

Protein Family

Fatty acid desaturase

UniProt Gene Name

FADS2

UniProt Synonym Gene Names

D6D; Delta(6) desaturase; Delta-6 desaturase

NCBI Protein Information

fatty acid desaturase 2

NCBI Summary for FADS2

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

UniProt Comments for FADS2

Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions. It catalizes as well the introduction of a cis double bond in palmitate to produce the mono-unsaturated fatty acid sapienate, the most abundant fatty acid in sebum.

Research Articles on FADS2

1. Our results demonstrate that FADS1-FADS2 are susceptibility genes for PCOS.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FADS2 elisa kit

Reference Product	PubMed Publications
ELOVL5 elisa kit	>34 publications with FADS2 and ELOVL5
ELOVL2 elisa kit	>24 publications with FADS2 and ELOVL2
ACSL1 elisa kit	>2 publications with FADS2 and ACSL1

Pathways associated with FADS2 elisa kit

Products by Pathway	Pathway Diagram
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis (6-desaturase) Pathway antibodies	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis (6-desaturase) Pathway Diagram
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis II (4-desaturase) Pathway antibodies	(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate Biosynthesis II (4-desaturase) Pathway Diagram
Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies	Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies	Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
Fatty Acid Metabolism Pathway antibodies	Fatty Acid Metabolism Pathway Diagram
Fatty Acid Metabolism Pathway antibodies	Fatty Acid Metabolism Pathway Diagram
Linoleic Acid (LA) Metabolism Pathway antibodies	Linoleic Acid (LA) Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
PPAR Signaling Pathway antibodies	PPAR Signaling Pathway Diagram

Diseases associated with FADS2 elisa kit

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>77 publications with FADS2 and Fatty Liver
Cardiovascular Diseases Antibodies	>32 publications with FADS2 and Cardiovascular Diseases
Inflammation Antibodies	>25 publications with FADS2 and Inflammation
Heart Diseases Antibodies	>19 publications with FADS2 and Heart Diseases
Liver Diseases Antibodies	>16 publications with FADS2 and Liver Diseases
Atherosclerosis Antibodies	>8 publications with FADS2 and Atherosclerosis
Nervous System Diseases Antibodies	>8 publications with FADS2 and Nervous System Diseases
Carcinoma, Hepatocellular Antibodies	>6 publications with FADS2 and Carcinoma, Hepatocellular
Hypertension Antibodies	>6 publications with FADS2 and Hypertension
Weight Gain Antibodies	>5 publications with FADS2 and Weight Gain

Organs/Tissues associated with FADS2 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>115 publications with FADS2 and Blood
Liver Antibodies	>86 publications with FADS2 and Liver
Brain Antibodies	>38 publications with FADS2 and Brain
Muscle Antibodies	>25 publications with FADS2 and Muscle
Adipose Tissue Antibodies	>23 publications with FADS2 and Adipose Tissue
Heart Antibodies	>22 publications with FADS2 and Heart
Connective Tissue Antibodies	>12 publications with FADS2 and Connective Tissue
Skin Antibodies	>12 publications with FADS2 and Skin
Vascular Antibodies	>8 publications with FADS2 and Vascular
Intestine Antibodies	>8 publications with FADS2 and Intestine