Hedgehog Homolog, Indian (IHH) ELISA Kit for Human

Name: Human IHH ELISA Kit; Hedgehog Homolog, Indian; MyBioSource
Brand: MyBioSource
SKU: MBS452499
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS452499

MBS452499 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Hedgehog Homolog, Indian (IHH) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Hedgehog Homolog, Indian (IHH), ELISA Kit

Full Product Name

Human Hedgehog Homolog, Indian (IHH) ELISA Kit

Product Gene Name

IHH elisa kit

Product Synonym Names

BDA1; HHG2

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue homogenates, cell lysates and other biological fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.057ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

45,251 Da

OMIM

AB018076 Genomic DNA

3D Structure

ModBase 3D Structure for Q14623

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of IHH elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IHH. It may not necessarily be applicable to this product.

NCBI GI #

119392086

NCBI GeneID

3549

NCBI Accession #

NP_002172.2

UniProt Primary Accession #

Q14623

UniProt Secondary Accession #

O43322; Q8N4B9; B9EGM5

UniProt Related Accession #

Q14623

GenBank Nucleotide #

NM_002181.3

NCBI Official Full Name

indian hedgehog protein preproprotein

NCBI Official Synonym Full Names

indian hedgehog

NCBI Official Symbol

IHH

NCBI Official Synonym Symbols

BDA1; HHG2

UniProt Protein Name

Indian hedgehog protein

UniProt Synonym Protein Names

HHG-2

Protein Family

Indian hedgehog protein

UniProt Gene Name

IHH

UniProt Synonym Gene Names

IHH

NCBI Protein Information

indian hedgehog protein

NCBI Summary for IHH

This gene encodes a member of the hedgehog family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including an N-terminal fragment that is involved in signaling. Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein encoded by this gene specifically plays a role in bone growth and differentiation. Mutations in this gene are the cause of brachydactyly type A1, which is characterized by shortening or malformation of the fingers and toes. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Nov 2015]

UniProt Comments for IHH

Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) ().

Research Articles on IHH

1. The serum levels of IHH and SHH were significantly higher in autistic subjects than those of control subjects. The findings support a correlation between SHH, IHH and BDNF in autistic children, suggesting their pathological role in autism.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IHH elisa kit

Reference Product	PubMed Publications
GLI1 elisa kit	>109 publications with IHH and GLI1
PTCH1 elisa kit	>86 publications with IHH and PTCH1
SMO elisa kit	>76 publications with IHH and SMO
BMP4 elisa kit	>32 publications with IHH and BMP4
BMP2 elisa kit	>30 publications with IHH and BMP2
PTHLH elisa kit	>26 publications with IHH and PTHLH
HHIP elisa kit	>18 publications with IHH and HHIP
PTCH2 elisa kit	>7 publications with IHH and PTCH2
BOC elisa kit	>3 publications with IHH and BOC
CDON elisa kit	>2 publications with IHH and CDON

Pathways associated with IHH elisa kit

Products by Pathway	Pathway Diagram
Activation Of SMO Pathway antibodies	Activation Of SMO Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Of Signal Transduction Pathway antibodies	Diseases Of Signal Transduction Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
HHAT G278V Abrogates Palmitoylation Of Hh-Np Pathway antibodies	HHAT G278V Abrogates Palmitoylation Of Hh-Np Pathway Diagram
Hedgehog 'on' State Pathway antibodies	Hedgehog 'on' State Pathway Diagram
Hedgehog Signaling Pathway antibodies	Hedgehog Signaling Pathway Diagram
Hedgehog Ligand Biogenesis Pathway antibodies	Hedgehog Ligand Biogenesis Pathway Diagram

Diseases associated with IHH elisa kit

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>147 publications with IHH and Congenital Abnormalities
Hypertrophy Antibodies	>109 publications with IHH and Hypertrophy
Infertility, Female Antibodies	>32 publications with IHH and Infertility, Female
Liver Diseases Antibodies	>31 publications with IHH and Liver Diseases
Brain Diseases Antibodies	>27 publications with IHH and Brain Diseases
Cardiovascular Diseases Antibodies	>27 publications with IHH and Cardiovascular Diseases
Brachydactyly type A1 Antibodies	>20 publications with IHH and Brachydactyly type A1
Fibrosis Antibodies	>20 publications with IHH and Fibrosis
Inflammation Antibodies	>15 publications with IHH and Inflammation
Liver Neoplasms Antibodies	>15 publications with IHH and Liver Neoplasms

Organs/Tissues associated with IHH elisa kit

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>149 publications with IHH and Embryonic Tissue
Kidney Antibodies	>28 publications with IHH and Kidney
Intestine Antibodies	>28 publications with IHH and Intestine
Uterus Antibodies	>26 publications with IHH and Uterus
Eye Antibodies	>19 publications with IHH and Eye
Prostate Antibodies	>15 publications with IHH and Prostate
Uncharacterized Tissue Antibodies	>4 publications with IHH and Uncharacterized Tissue