Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit for Human

Name: Human CYR61 ELISA Kit; Cysteine Rich Protein, Angiogenic Inducer 61; MyBioSource
Brand: MyBioSource
SKU: MBS452751
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS452751

MBS452751 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit target analytes in biological samples. The concentration… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61), ELISA Kit

Full Product Name

Human Cysteine Rich Protein, Angiogenic Inducer 61 (CYR61) ELISA Kit

Product Gene Name

CYR61 elisa kit

Product Synonym Names

CCN1; GIG1; IGFBP10; CCN family member 1; Insulin-like growth factor-binding protein 10

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Detection Range

31.25-2000pg/mL

Sensitivity

13.4pg/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

42,027 Da

OMIM

U62015 mRNA

3D Structure

ModBase 3D Structure for O00622

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of CYR61 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYR61. It may not necessarily be applicable to this product.

NCBI GI #

31542331

NCBI GeneID

3491

NCBI Accession #

NP_001545.2

UniProt Primary Accession #

O00622

UniProt Secondary Accession #

O14934; O43775; Q9BZL7

UniProt Related Accession #

O00622

GenBank Nucleotide #

NM_001554.4

NCBI Official Full Name

protein CYR61

NCBI Official Synonym Full Names

cysteine rich angiogenic inducer 61

NCBI Official Symbol

CYR61

NCBI Official Synonym Symbols

CCN1; GIG1; IGFBP10

UniProt Protein Name

Protein CYR61

UniProt Synonym Protein Names

CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10; Protein GIG1

Protein Family

Protein

UniProt Gene Name

CYR61

UniProt Synonym Gene Names

CCN1; GIG1; IGFBP10; IBP-10; IGF-binding protein 10; IGFBP-10

NCBI Protein Information

protein CYR61

NCBI Summary for CYR61

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]

UniProt Comments for CYR61

Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Research Articles on CYR61

1. up-regulated in epithelial cells of salivary glands of primary Sjogren's syndrome patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CYR61 elisa kit

Reference Product	PubMed Publications
JUN elisa kit	>100 publications with CYR61 and JUN
FOS elisa kit	>20 publications with CYR61 and FOS
CTNNB1 elisa kit	>18 publications with CYR61 and CTNNB1
RHOA elisa kit	>11 publications with CYR61 and RHOA
MKL1 elisa kit	>7 publications with CYR61 and MKL1
SRF elisa kit	>6 publications with CYR61 and SRF
ITGAV elisa kit	>1 publications with CYR61 and ITGAV

Pathways associated with CYR61 elisa kit

Products by Pathway	Pathway Diagram
Hypertrophy Model Pathway antibodies	Hypertrophy Model Pathway Diagram
Oncostatin M Signaling Pathway antibodies	Oncostatin M Signaling Pathway Diagram
Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies	Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
RhoA Signaling Pathway antibodies	RhoA Signaling Pathway Diagram
Amb2 Integrin Signaling Pathway antibodies	Amb2 Integrin Signaling Pathway Diagram

Diseases associated with CYR61 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>76 publications with CYR61 and Inflammation
Disease Models, Animal Antibodies	>59 publications with CYR61 and Disease Models, Animal
Fibrosis Antibodies	>51 publications with CYR61 and Fibrosis
Neoplasm Metastasis Antibodies	>50 publications with CYR61 and Neoplasm Metastasis
Breast Neoplasms Antibodies	>48 publications with CYR61 and Breast Neoplasms
Nervous System Diseases Antibodies	>35 publications with CYR61 and Nervous System Diseases
Lung Diseases Antibodies	>33 publications with CYR61 and Lung Diseases
Necrosis Antibodies	>29 publications with CYR61 and Necrosis
Brain Diseases Antibodies	>26 publications with CYR61 and Brain Diseases
Neoplasms, Experimental Antibodies	>25 publications with CYR61 and Neoplasms, Experimental

Organs/Tissues associated with CYR61 elisa kit

Organ/Tissue Name	Pubmed Publications
Connective Tissue Antibodies	>203 publications with CYR61 and Connective Tissue
Vascular Antibodies	>150 publications with CYR61 and Vascular
Bone Antibodies	>95 publications with CYR61 and Bone
Muscle Antibodies	>89 publications with CYR61 and Muscle
Embryonic Tissue Antibodies	>59 publications with CYR61 and Embryonic Tissue
Lung Antibodies	>55 publications with CYR61 and Lung
Brain Antibodies	>46 publications with CYR61 and Brain
Skin Antibodies	>39 publications with CYR61 and Skin
Liver Antibodies	>38 publications with CYR61 and Liver
Prostate Antibodies	>34 publications with CYR61 and Prostate