Interleukin 1 Zeta (IL1z) ELISA Kit for Human

Name: Human IL1z ELISA Kit; Interleukin 1 Zeta; MyBioSource
Brand: MyBioSource
SKU: MBS453413
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS453413

MBS453413 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 1 Zeta (IL1z) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$370 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 1 Zeta (IL1z), ELISA Kit

Full Product Name

Human Interleukin 1 Zeta (IL1z) ELISA Kit

Product Gene Name

IL1z elisa kit

Product Synonym Names

IL1F7; IL37; FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H4; IL-1RP1; IL1H4; IL1RP1; Interleukin 37; Interleukin-1-Related Protein; Interleukin 1 Family, Member 7

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Detection Range

78.125-5000pg/mL

Sensitivity

24pg/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

17,459 Da

OMIM

AF200496 mRNA

3D Structure

ModBase 3D Structure for Q9NZH6

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of IL1z elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL1z. It may not necessarily be applicable to this product.

NCBI GI #

20127524

NCBI GeneID

27178

NCBI Accession #

NP_055254.2

UniProt Primary Accession #

Q9NZH6

UniProt Secondary Accession #

Q56AP9; Q8TD04; Q8TD05; Q9HBF2; Q9HBF3; Q9UHA6; B5BU97

UniProt Related Accession #

Q9NZH6

GenBank Nucleotide #

NM_014439.3

NCBI Official Full Name

interleukin-37 isoform 1

NCBI Official Synonym Full Names

interleukin 37

NCBI Official Symbol

IL37

NCBI Official Synonym Symbols

FIL1; FIL1Z; IL-1H; IL-37; IL1F7; IL1H4; IL-1F7; IL-1H4; IL1RP1; IL-1RP1; FIL1(ZETA)

UniProt Protein Name

Interleukin-37

UniProt Synonym Protein Names

FIL1 zeta; IL-1X; Interleukin-1 family member 7; IL-1F7; Interleukin-1 homolog 4; IL-1H; IL-1H4; Interleukin-1 zeta; IL-1 zeta; Interleukin-1-related protein; IL-1RP1; Interleukin-23; IL-37

UniProt Gene Name

IL37

UniProt Synonym Gene Names

FIL1Z; IL1F7; IL1H4; IL1RP1; IL-1F7; IL-1H; IL-1H4; IL-1 zeta; IL-1RP1; IL-37

NCBI Protein Information

interleukin-37

NCBI Summary for IL1z

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

UniProt Comments for IL1z

Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Research Articles on IL1z

1. These fi ndings suggest that elevation of HLA-G and IL-37 in hepatitis C virus may play an important role in response to combined therapy with interferon-apha and ribovirin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL1z elisa kit

Reference Product	PubMed Publications
SMAD3 elisa kit	>4 publications with IL1z and SMAD3
IL6 elisa kit	>3 publications with IL1z and IL6
IL8 elisa kit	>2 publications with IL1z and IL8

Pathways associated with IL1z elisa kit

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Signaling By Interleukins Pathway antibodies	Signaling By Interleukins Pathway Diagram

Diseases associated with IL1z elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>50 publications with IL1z and Inflammation
Necrosis Antibodies	>13 publications with IL1z and Necrosis
Cardiovascular Diseases Antibodies	>10 publications with IL1z and Cardiovascular Diseases
Disease Models, Animal Antibodies	>10 publications with IL1z and Disease Models, Animal
Lung Diseases Antibodies	>7 publications with IL1z and Lung Diseases
Heart Diseases Antibodies	>6 publications with IL1z and Heart Diseases
Liver Diseases Antibodies	>6 publications with IL1z and Liver Diseases
Respiratory Hypersensitivity Antibodies	>4 publications with IL1z and Respiratory Hypersensitivity
Death Antibodies	>3 publications with IL1z and Death
Carcinoma, Hepatocellular Antibodies	>2 publications with IL1z and Carcinoma, Hepatocellular

Organs/Tissues associated with IL1z elisa kit

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>4 publications with IL1z and Intestine
Placenta Antibodies	>1 publications with IL1z and Placenta