Lysophosphatidylcholine Acyltransferase 3 (LPCAT3) ELISA Kit for Human

Name: Human LPCAT3 ELISA Kit; Lysophosphatidylcholine Acyltransferase 3; MyBioSource
Brand: MyBioSource
SKU: MBS453954
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS453954

MBS453954 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Lysophosphatidylcholine Acyltransferase 3 (LPCAT3) ELISA Kit target analytes in biological samples. The concentration… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Lysophosphatidylcholine Acyltransferase 3 (LPCAT3), ELISA Kit

Full Product Name

Human Lysophosphatidylcholine Acyltransferase 3 (LPCAT3) ELISA Kit

Product Gene Name

LPCAT3 elisa kit

Product Synonym Names

MBOAT5; C3F; OACT5; Nessy; LPSAT; Membrane Bound O-AcylTransferase Domain Containing 5; Lysophospholipid Acyltransferase 5; Lysophosphatidylserine acyltransferase

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

3.125-200ng/mL

Sensitivity

1.29ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

46,765 Da

OMIM

BX648009 mRNA

3D Structure

ModBase 3D Structure for Q6P1A2

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of LPCAT3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LPCAT3. It may not necessarily be applicable to this product.

NCBI GI #

42542394

NCBI GeneID

10162

NCBI Accession #

NP_005759.4

UniProt Primary Accession #

Q6P1A2

UniProt Secondary Accession #

Q7KZS1; Q92980; Q9BW40; B2RDH0; B7Z3N3

UniProt Related Accession #

Q6P1A2

GenBank Nucleotide #

NM_005768.5

NCBI Official Full Name

lysophospholipid acyltransferase 5

NCBI Official Synonym Full Names

lysophosphatidylcholine acyltransferase 3

NCBI Official Symbol

LPCAT3

NCBI Official Synonym Symbols

C3F; LPCAT; LPSAT; OACT5; nessy; MBOAT5; LPLAT 5

UniProt Protein Name

Lysophospholipid acyltransferase 5

UniProt Synonym Protein Names

1-acylglycerophosphocholine O-acyltransferase (EC:2.3.1.23); 1-acylglycerophosphoserine O-acyltransferase (EC:2.3.1.n6); Lysophosphatidylcholine acyltransferase; LPCAT; Lyso-PC acyltransferase; Lysophosphatidylcholine acyltransferase 3; Lyso-PC acyltransferase 3; Lysophosphatidylserine acyltransferase; LPSAT; Lyso-PS acyltransferase; Membrane-bound O-acyltransferase domain-containing protein 5; O-acyltransferase domain-containing protein 5

Protein Family

Lysophospholipid acyltransferase

UniProt Gene Name

LPCAT3

UniProt Synonym Gene Names

MBOAT5; OACT5; LPLAT 5; LPCAT; Lyso-PC acyltransferase; Lyso-PC acyltransferase 3; LPSAT; Lyso-PS acyltransferase; O-acyltransferase domain-containing protein 5

NCBI Protein Information

lysophospholipid acyltransferase 5

UniProt Comments for LPCAT3

Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). Catalyzes also the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L-serine or PS) (LPSAT activity). Has also weak lysophosphatidylethanolamine acyltransferase activity (LPEAT activity). Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Seems to be the major enzyme contributing to LPCAT activity in the liver. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.

Research Articles on LPCAT3

1. Our findings suggest that LPCAT3 plays an important role in M1/M2-macrophage polarization, providing novel potential therapeutic targets for the regulation of immune and inflammatory disorders

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LPCAT3 elisa kit

Reference Product	PubMed Publications
LPCAT1 elisa kit	>3 publications with LPCAT3 and LPCAT1
LPCAT2 elisa kit	>2 publications with LPCAT3 and LPCAT2

Pathways associated with LPCAT3 elisa kit

Products by Pathway	Pathway Diagram
Acyl Chain Remodelling Of PC Pathway antibodies	Acyl Chain Remodelling Of PC Pathway Diagram
Acyl Chain Remodelling Of PE Pathway antibodies	Acyl Chain Remodelling Of PE Pathway Diagram
Acyl Chain Remodelling Of PS Pathway antibodies	Acyl Chain Remodelling Of PS Pathway Diagram
CDP-diacylglycerol Biosynthesis Pathway antibodies	CDP-diacylglycerol Biosynthesis Pathway Diagram
Glycerophospholipid Biosynthesis Pathway antibodies	Glycerophospholipid Biosynthesis Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Glycerophospholipid Metabolism Pathway antibodies	Glycerophospholipid Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Lipids And Lipoproteins Pathway antibodies	Metabolism Of Lipids And Lipoproteins Pathway Diagram
Phospholipid Metabolism Pathway antibodies	Phospholipid Metabolism Pathway Diagram

Diseases associated with LPCAT3 elisa kit

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>12 publications with LPCAT3 and Fatty Liver
Inflammation Antibodies	>6 publications with LPCAT3 and Inflammation
Liver Diseases Antibodies	>3 publications with LPCAT3 and Liver Diseases
Insulin Resistance Antibodies	>2 publications with LPCAT3 and Insulin Resistance
Cardiovascular Diseases Antibodies	>1 publications with LPCAT3 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>1 publications with LPCAT3 and Disease Models, Animal
Hypertrophy Antibodies	>1 publications with LPCAT3 and Hypertrophy
Fibrosis Antibodies	>1 publications with LPCAT3 and Fibrosis
Hepatomegaly Antibodies	>1 publications with LPCAT3 and Hepatomegaly
Weight Loss Antibodies	>1 publications with LPCAT3 and Weight Loss

Organs/Tissues associated with LPCAT3 elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>16 publications with LPCAT3 and Liver
Blood Antibodies	>7 publications with LPCAT3 and Blood
Intestine Antibodies	>5 publications with LPCAT3 and Intestine
Kidney Antibodies	>2 publications with LPCAT3 and Kidney
Brain Antibodies	>2 publications with LPCAT3 and Brain
Pancreas Antibodies	>1 publications with LPCAT3 and Pancreas
Heart Antibodies	>1 publications with LPCAT3 and Heart
Placenta Antibodies	>1 publications with LPCAT3 and Placenta