Proliferation Associated Protein 2g4 (PA2G4) ELISA Kit for Human

Name: Human PA2G4 ELISA Kit; Proliferation Associated Protein 2g4; MyBioSource
Brand: MyBioSource
SKU: MBS454476
Price: 555 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS454476

MBS454476 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Proliferation Associated Protein 2G4 (PA2G4) ELISA Kit target analytes in biological samples. The concentration… More details

$555 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Proliferation Associated Protein 2G4 (PA2G4), ELISA Kit

Full Product Name

Human Proliferation Associated Protein 2G4 (PA2G4) ELISA Kit

Product Gene Name

PA2G4 elisa kit

Species Reactivity

Human

Assay Type

Sandwich

Samples

Tissue homogenates, cell lysates and other biological fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.113ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

38,059 Da

OMIM

U59435 mRNA

3D Structure

ModBase 3D Structure for Q9UQ80

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of PA2G4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PA2G4. It may not necessarily be applicable to this product.

NCBI GI #

124494254

NCBI GeneID

5036

NCBI Accession #

NP_006182.2

UniProt Primary Accession #

Q9UQ80

UniProt Secondary Accession #

O43846; Q9UM59

UniProt Related Accession #

Q9UQ80

GenBank Nucleotide #

NM_006191.2

NCBI Official Full Name

proliferation-associated protein 2G4

NCBI Official Synonym Full Names

proliferation-associated 2G4

NCBI Official Symbol

PA2G4

NCBI Official Synonym Symbols

EBP1; HG4-1; p38-2G4

UniProt Protein Name

Proliferation-associated protein 2G4

UniProt Synonym Protein Names

Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1

Protein Family

Proliferation-associated protein

UniProt Gene Name

PA2G4

UniProt Synonym Gene Names

EBP1; hG4-1

NCBI Protein Information

proliferation-associated protein 2G4

NCBI Summary for PA2G4

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]

UniProt Comments for PA2G4

May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation ().

Research Articles on PA2G4

1. The combined determination of Ebp1 and p53 expression levels in cervical cancer patients could support the effective prediction of metastatic potential and patient prognosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PA2G4 elisa kit

Reference Product	PubMed Publications
ERBB3 elisa kit	>45 publications with PA2G4 and ERBB3

Pathways associated with PA2G4 elisa kit

Products by Pathway	Pathway Diagram
Coregulation Of Androgen Receptor Activity Pathway antibodies	Coregulation Of Androgen Receptor Activity Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Neutrophil Degranulation Pathway antibodies	Neutrophil Degranulation Pathway Diagram

Diseases associated with PA2G4 elisa kit

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>14 publications with PA2G4 and Breast Neoplasms
Disease Progression Antibodies	>9 publications with PA2G4 and Disease Progression
Adenocarcinoma Antibodies	>7 publications with PA2G4 and Adenocarcinoma
Disease Models, Animal Antibodies	>4 publications with PA2G4 and Disease Models, Animal
Inflammation Antibodies	>4 publications with PA2G4 and Inflammation
Neoplasms, Experimental Antibodies	>3 publications with PA2G4 and Neoplasms, Experimental
Carcinoma, Hepatocellular Antibodies	>3 publications with PA2G4 and Carcinoma, Hepatocellular
Lung Neoplasms Antibodies	>3 publications with PA2G4 and Lung Neoplasms
Nervous System Diseases Antibodies	>3 publications with PA2G4 and Nervous System Diseases
Necrosis Antibodies	>3 publications with PA2G4 and Necrosis

Organs/Tissues associated with PA2G4 elisa kit

Organ/Tissue Name	Pubmed Publications
Prostate Antibodies	>15 publications with PA2G4 and Prostate
Blood Antibodies	>8 publications with PA2G4 and Blood
Muscle Antibodies	>5 publications with PA2G4 and Muscle
Salivary Gland Antibodies	>4 publications with PA2G4 and Salivary Gland
Mouth Antibodies	>4 publications with PA2G4 and Mouth
Lung Antibodies	>4 publications with PA2G4 and Lung
Brain Antibodies	>4 publications with PA2G4 and Brain
Embryonic Tissue Antibodies	>3 publications with PA2G4 and Embryonic Tissue
Liver Antibodies	>3 publications with PA2G4 and Liver
Kidney Antibodies	>2 publications with PA2G4 and Kidney