Alpha-1-Microglobulin/Bikunin Precursor (a1M) ELISA Kit for Mouse

Name: Mouse a1M ELISA Kit; Alpha-1-Microglobulin/Bikunin Precursor; MyBioSource
Brand: MyBioSource
SKU: MBS454621
Price: 485 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS454621

MBS454621 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Alpha-1-Microglobulin/Bikunin Precursor (a1M) ELISA Kit target analytes in biological samples. The concentration… More details

$485 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Alpha-1-Microglobulin/Bikunin Precursor (a1M), ELISA Kit

Full Product Name

Mouse Alpha-1-Microglobulin/Bikunin Precursor (a1M) ELISA Kit

Product Gene Name

a1M elisa kit

Product Synonym Names

AMBP; UTI; HCP; EDC1; HI30; IATIL; ITILC; ITI; ITIL; Alpha 1 Microglobulin/Bikunin Precursor; Growth-inhibiting protein 19; Uristatin; Uronic-Acid-Rich Protein; Trypstatin

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, plasma and other biological fluids.

Detection Range

1.56-100ng/mL

Sensitivity

0.52ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

39,029 Da

3D Structure

ModBase 3D Structure for Q07456

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of a1M elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for a1M. It may not necessarily be applicable to this product.

NCBI GI #

6680684

NCBI GeneID

11699

NCBI Accession #

NP_031469.1

UniProt Primary Accession #

Q07456

UniProt Secondary Accession #

Q61294; Q925W1; Q9DBJ9

UniProt Related Accession #

Q07456

GenBank Nucleotide #

NM_007443.4

NCBI Official Full Name

protein AMBP preproprotein

NCBI Official Synonym Full Names

alpha 1 microglobulin/bikunin

NCBI Official Symbol

Ambp

NCBI Official Synonym Symbols

UTI; ASPI; Itil; HI-30; Intin4; AI194774

UniProt Protein Name

Protein AMBP

UniProt Synonym Protein Names

Alpha-1-microglobulinInter-alpha-trypsin inhibitor light chain; ITI-LC

Protein Family

Alpha-1-macroglobulin

UniProt Gene Name

Ambp

UniProt Synonym Gene Names

Itil; ITI-LC

NCBI Protein Information

protein AMBP

NCBI Summary for a1M

This gene encodes a fusion protein that undergoes proteolytic processing to generate two mature proteins: alpha-1-microglobulin (A1m) is a heme-binding plasma glycoprotein of the lipocalin superfamily of proteins that bind to hydrophobic molecules, whereas bikunin belongs to the superfamily of Kunitz-type protease inhibitors. The transgenic mice specifically lacking bikunin, but not A1m, exhibit female infertility and an increased sensitivity to lung metastasis. [provided by RefSeq, Oct 2015]

UniProt Comments for a1M

Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization ().

Research Articles on a1M

1. In this review, the use of genetically targeted mice selectively lacking UTI provides evidence of a therapeutic option for experimental endotoxin-related inflammatory disorders such as acute lung injury and acute liver injury.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with a1M elisa kit

Reference Product	PubMed Publications
Serpinc1 elisa kit	>2 publications with a1M and Serpinc1
Fgg elisa kit	>1 publications with a1M and Fgg
Itih3 elisa kit	>1 publications with a1M and Itih3
Itih1 elisa kit	>1 publications with a1M and Itih1

Pathways associated with a1M elisa kit

Products by Pathway	Pathway Diagram
Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies	Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
Scavenging Of Heme From Plasma Pathway antibodies	Scavenging Of Heme From Plasma Pathway Diagram
Vesicle-mediated Transport Pathway antibodies	Vesicle-mediated Transport Pathway Diagram

Diseases associated with a1M elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>65 publications with a1M and Cardiovascular Diseases
Hypertension Antibodies	>49 publications with a1M and Hypertension
Inflammation Antibodies	>23 publications with a1M and Inflammation
Necrosis Antibodies	>16 publications with a1M and Necrosis
Kidney Diseases Antibodies	>14 publications with a1M and Kidney Diseases
Heart Diseases Antibodies	>12 publications with a1M and Heart Diseases
Hemorrhage Antibodies	>9 publications with a1M and Hemorrhage
Liver Diseases Antibodies	>7 publications with a1M and Liver Diseases
Drug-Induced Liver Injury Antibodies	>6 publications with a1M and Drug-Induced Liver Injury
Disease Models, Animal Antibodies	>5 publications with a1M and Disease Models, Animal

Organs/Tissues associated with a1M elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>30 publications with a1M and Liver
Kidney Antibodies	>24 publications with a1M and Kidney
Muscle Antibodies	>7 publications with a1M and Muscle
Lung Antibodies	>5 publications with a1M and Lung
Pancreas Antibodies	>3 publications with a1M and Pancreas
Embryonic Tissue Antibodies	>2 publications with a1M and Embryonic Tissue
Eye Antibodies	>1 publications with a1M and Eye
Lymph Node Antibodies	>1 publications with a1M and Lymph Node