Protein Z (PROZ) ELISA Kit for Human

Name: Human PROZ ELISA Kit; Protein Z; MyBioSource
Brand: MyBioSource
SKU: MBS454633
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS454633

MBS454633 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein Z (PROZ) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$480 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Protein Z (PROZ), ELISA Kit

Full Product Name

Human Protein Z (PROZ) ELISA Kit

Product Gene Name

PROZ elisa kit

Product Synonym Names

PRO-Z; PZ; Vitamin K Dependent Protein Z; VKDPZ; VKDP-Z

Species Reactivity

Human

Assay Type

Sandwich

Samples

Plasma.

Detection Range

0.156-10ng/mL

Sensitivity

0.073ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

47,053 Da

OMIM

M55670 mRNA

3D Structure

ModBase 3D Structure for P22891

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of PROZ elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PROZ. It may not necessarily be applicable to this product.

NCBI GI #

371502106

NCBI GeneID

8858

NCBI Accession #

NP_001243063.1

UniProt Primary Accession #

P22891

UniProt Secondary Accession #

Q15213; Q5JVF5; Q5JVF6; A6NMB4

UniProt Related Accession #

P22891

GenBank Nucleotide #

NM_001256134.1

NCBI Official Full Name

vitamin K-dependent protein Z isoform 1

NCBI Official Synonym Full Names

protein Z, vitamin K dependent plasma glycoprotein

NCBI Official Symbol

PROZ

NCBI Official Synonym Symbols

UniProt Protein Name

Vitamin K-dependent protein Z

Protein Family

Vitamin K-dependent protein

UniProt Gene Name

PROZ

NCBI Protein Information

vitamin K-dependent protein Z

NCBI Summary for PROZ

This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

UniProt Comments for PROZ

Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.

Research Articles on PROZ

1. There was no significant difference in the clinical features of the patients with and without the polymorphism. We therefore conclude that PZ G79A polymorphism is not a risk factor for puerperal CVT in Indian women.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PROZ elisa kit

Reference Product	PubMed Publications
SERPINC1 elisa kit	>2 publications with PROZ and SERPINC1
GGCX elisa kit	>1 publications with PROZ and GGCX
SERPINA10 elisa kit	>1 publications with PROZ and SERPINA10

Pathways associated with PROZ elisa kit

Products by Pathway	Pathway Diagram
Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway antibodies	Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway Diagram
Gamma-carboxylation Of Protein Precursors Pathway antibodies	Gamma-carboxylation Of Protein Precursors Pathway Diagram
Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway antibodies	Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway Diagram
Metabolism Of Proteins Pathway antibodies	Metabolism Of Proteins Pathway Diagram
Post-translational Protein Modification Pathway antibodies	Post-translational Protein Modification Pathway Diagram
Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway antibodies	Removal Of Aminoterminal Propeptides From Gamma-carboxylated Proteins Pathway Diagram
Transport Of Gamma-carboxylated Protein Precursors From The Endoplasmic Reticulum To The Golgi Apparatus Pathway antibodies	Transport Of Gamma-carboxylated Protein Precursors From The Endoplasmic Reticulum To The Golgi Apparatus Pathway Diagram

Diseases associated with PROZ elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>3 publications with PROZ and Cardiovascular Diseases
Congenital Abnormalities Antibodies	>1 publications with PROZ and Congenital Abnormalities
Heart Diseases Antibodies	>1 publications with PROZ and Heart Diseases
Inflammation Antibodies	>1 publications with PROZ and Inflammation

Organs/Tissues associated with PROZ elisa kit

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>3 publications with PROZ and Liver