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Cytovillin (CVL) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455084

MBS455084 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cytovillin (CVL) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cytovillin (CVL), ELISA Kit
Full Product Name
Human Cytovillin (CVL) ELISA Kit
Product Gene Name
CVL elisa kit
Product Synonym Names
EZR; Ezrin; VIL2; CVIL; CVL; Villin 2; p81
Species Reactivity
Human
Assay Type
Sandwich
Samples
Tissue homogenates, cell lysates and other biological fluids.
Detection Range
0.312-20ng/mL
Sensitivity
0.114ng/mL
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
Molecular Weight
69,413 Da
OMIM
X51521 mRNA
3D Structure
ModBase 3D Structure for P15311
Intra Assay
CV<10%
Inter Assay
CV<12%
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of CVL elisa kit

Human CVL ELISA Kit – Cat# MBS455084

Other Notes

Small volumes of CVL elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CVL. It may not necessarily be applicable to this product.

NCBI GI #
161702986
NCBI GeneID
7430
NCBI Accession #
NP_001104547.1
UniProt Primary Accession #
P15311
UniProt Secondary Accession #
P23714; Q4VX75; Q96CU8; Q9NSJ4; E1P5A8
UniProt Related Accession #
P15311
GenBank Nucleotide #
NM_001111077.1
NCBI Official Full Name
ezrin
NCBI Official Synonym Full Names
ezrin
NCBI Official Symbol
EZR
NCBI Official Synonym Symbols
CVL; CVIL; VIL2; HEL-S-105
UniProt Protein Name
Ezrin
UniProt Synonym Protein Names
Cytovillin; Villin-2; p81
UniProt Gene Name
EZR
UniProt Synonym Gene Names
VIL2
NCBI Protein Information
ezrin

NCBI Summary for CVL

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CVL

Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.

Research Articles on CVL

1. Phosphorylation of ezrin together with its binding to phosphatidylinositol-4,5-bisphosphate tethers the F508del CFTR to the actin cytoskeleton, stabilizing it on the apical membrane and rescuing the sub-membrane compartmentalization of cAMP and activated PKA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CVL elisa kit

 Reference Product  PubMed Publications
 PRKCA elisa kit  >3 publications with CVL and PRKCA
 ICAM1 elisa kit  >1 publications with CVL and ICAM1
 SLC9A3R1 elisa kit  >1 publications with CVL and SLC9A3R1

Pathways associated with CVL elisa kit

 Products by Pathway  Pathway Diagram
 AGE/RAGE Pathway antibodies  AGE/RAGE Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 FAS (CD95) Signaling Pathway antibodies  FAS (CD95) Signaling Pathway Diagram
 Gastric Acid Secretion Pathway antibodies  Gastric Acid Secretion Pathway Diagram
 Gastric Acid Secretion Pathway antibodies  Gastric Acid Secretion Pathway Diagram
 L1CAM Interactions Pathway antibodies  L1CAM Interactions Pathway Diagram
 LKB1 Signaling Events Pathway antibodies  LKB1 Signaling Events Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram

Diseases associated with CVL elisa kit

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >17 publications with CVL and Carcinoma
 Lung Neoplasms Antibodies  >10 publications with CVL and Lung Neoplasms
 Neoplasm Metastasis Antibodies  >7 publications with CVL and Neoplasm Metastasis
 Brain Diseases Antibodies  >5 publications with CVL and Brain Diseases
 Inflammation Antibodies  >3 publications with CVL and Inflammation
 Nervous System Diseases Antibodies  >3 publications with CVL and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with CVL and Cell Transformation, Neoplastic
 Disease Models, Animal Antibodies  >2 publications with CVL and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >2 publications with CVL and Neoplasms, Experimental
 Liver Diseases Antibodies  >2 publications with CVL and Liver Diseases

Organs/Tissues associated with CVL elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >14 publications with CVL and Lung
 Bone Antibodies  >5 publications with CVL and Bone
 Blood Antibodies  >5 publications with CVL and Blood
 Lymph Node Antibodies  >4 publications with CVL and Lymph Node
 Lymph Antibodies  >4 publications with CVL and Lymph
 Brain Antibodies  >4 publications with CVL and Brain
 Eye Antibodies  >3 publications with CVL and Eye
 Vascular Antibodies  >3 publications with CVL and Vascular
 Thyroid Antibodies  >3 publications with CVL and Thyroid
 Liver Antibodies  >2 publications with CVL and Liver
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