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Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455423

MBS455423 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit target analytes in biological samples. The concentration… More details

$395 / 48 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Macrophage Inflammatory Protein 1 Alpha (MIP1a), ELISA Kit
Full Product Name
Human Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit
Product Gene Name
MIP1a elisa kit
Product Synonym Names
CCL3; MIP1-A; SCYA3; Chemokine C-C-Motif Ligand 3; Small Inducible Cytokine A3; Homologous To Mouse Mip-1a; Tonsillar Lymphocyte LD78 Alpha Protein
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Detection Range
15.625-1000pg/mL
Sensitivity
5.9pg/mL
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
Molecular Weight
10,085 Da
OMIM
D00044 mRNA
3D Structure
ModBase 3D Structure for P10147
Intra Assay
CV<10%
Inter Assay
CV<12%
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Typical Standard Curve/Testing Data of MIP1a elisa kit

Human MIP1a ELISA Kit – Cat# MBS455423

Other Notes

Small volumes of MIP1a elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MIP1a. It may not necessarily be applicable to this product.

NCBI GI #
4506843
NCBI GeneID
6348
NCBI Accession #
NP_002974.1
UniProt Primary Accession #
P10147
UniProt Related Accession #
P10147
GenBank Nucleotide #
NM_002983.2
NCBI Official Full Name
C-C motif chemokine 3
NCBI Official Synonym Full Names
C-C motif chemokine ligand 3
NCBI Official Symbol
CCL3
NCBI Official Synonym Symbols
MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
UniProt Protein Name
C-C motif chemokine 3
UniProt Synonym Protein Names
G0/G1 switch regulatory protein 19-1; Macrophage inflammatory protein 1-alpha; MIP-1-alpha
Protein Family
B-box domain protein
UniProt Gene Name
CCL3
UniProt Synonym Gene Names
G0S19-1; MIP1A; SCYA3; MIP-1-alpha
NCBI Protein Information
C-C motif chemokine 3

NCBI Summary for MIP1a

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
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UniProt Comments for MIP1a

Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

Research Articles on MIP1a

1. we demonstrate an association of CCL3 expression by CLL cells with increased numbers of CD3+ T cells and CD57+ cells in the lymph node microenvironment, which may promote CLL cell survival and proliferation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MIP1a elisa kit

 Reference Product  PubMed Publications
 CCL4 elisa kit  >1732 publications with MIP1a and CCL4
 CCR5 elisa kit  >548 publications with MIP1a and CCR5
 CCR1 elisa kit  >300 publications with MIP1a and CCR1
 CCR2 elisa kit  >155 publications with MIP1a and CCR2
 CCR3 elisa kit  >74 publications with MIP1a and CCR3
 CCR4 elisa kit  >52 publications with MIP1a and CCR4
 CXCR5 elisa kit  >6 publications with MIP1a and CXCR5
 IL12B elisa kit  >5 publications with MIP1a and IL12B
 IDE elisa kit  >5 publications with MIP1a and IDE
 CCBP2 elisa kit  >4 publications with MIP1a and CCBP2

Pathways associated with MIP1a elisa kit

 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interleukin-10 Signaling Pathway antibodies  Interleukin-10 Signaling Pathway Diagram

Diseases associated with MIP1a elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1053 publications with MIP1a and Inflammation
 Necrosis Antibodies  >579 publications with MIP1a and Necrosis
 Disease Models, Animal Antibodies  >367 publications with MIP1a and Disease Models, Animal
 Lung Diseases Antibodies  >271 publications with MIP1a and Lung Diseases
 Cardiovascular Diseases Antibodies  >199 publications with MIP1a and Cardiovascular Diseases
 HIV Infections Antibodies  >196 publications with MIP1a and HIV Infections
 Hypersensitivity Antibodies  >111 publications with MIP1a and Hypersensitivity
 Liver Diseases Antibodies  >108 publications with MIP1a and Liver Diseases
 Fibrosis Antibodies  >95 publications with MIP1a and Fibrosis
 Pneumonia Antibodies  >78 publications with MIP1a and Pneumonia

Organs/Tissues associated with MIP1a elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1712 publications with MIP1a and Blood
 Lung Antibodies  >375 publications with MIP1a and Lung
 Brain Antibodies  >292 publications with MIP1a and Brain
 Liver Antibodies  >239 publications with MIP1a and Liver
 Kidney Antibodies  >94 publications with MIP1a and Kidney
 Heart Antibodies  >94 publications with MIP1a and Heart
 Intestine Antibodies  >68 publications with MIP1a and Intestine
 Eye Antibodies  >58 publications with MIP1a and Eye
 Uterus Antibodies  >23 publications with MIP1a and Uterus
 Placenta Antibodies  >21 publications with MIP1a and Placenta
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