Prostaglandin Endoperoxide Synthase 1 (PTGS1) ELISA Kit for Human

Name: Human PTGS1 ELISA Kit; Prostaglandin Endoperoxide Synthase 1; MyBioSource
Brand: MyBioSource
SKU: MBS455428
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455428

MBS455428 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostaglandin Endoperoxide Synthase 1 (PTGS1) ELISA Kit target analytes in biological samples. The concentration… More details

$480 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Prostaglandin Endoperoxide Synthase 1 (PTGS1), ELISA Kit

Full Product Name

Human Prostaglandin Endoperoxide Synthase 1 (PTGS1) ELISA Kit

Product Gene Name

PTGS1 elisa kit

Product Synonym Names

COX1 COX3 PCOX1 PGG/HS PGHS1 PHS1 PTGHS Cyclooxygenase 1 Prostaglandin H2 Synthase 1 Prostaglandin G/H Synthase And Cyclooxygenase

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

0.625-40ng/mL

Sensitivity

0.241ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

72,010 Da

3D Structure

ModBase 3D Structure for P23219

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of PTGS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTGS1. It may not necessarily be applicable to this product.

NCBI GI #

18104967

NCBI GeneID

5742

NCBI Accession #

NP_000953.2

UniProt Primary Accession #

P23219

UniProt Secondary Accession #

Q15122; Q3HY28; Q3HY29; Q5T7T6; Q5T7T7; Q5T7T8; A8K1V7; B4DHQ2; B4E2S5

UniProt Related Accession #

P23219

GenBank Nucleotide #

NM_000962.3

NCBI Official Full Name

prostaglandin G/H synthase 1 isoform 1

NCBI Official Synonym Full Names

prostaglandin-endoperoxide synthase 1

NCBI Official Symbol

PTGS1

NCBI Official Synonym Symbols

COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1

UniProt Protein Name

Prostaglandin G/H synthase 1

UniProt Synonym Protein Names

Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1

Protein Family

Prostaglandin G/H synthase

UniProt Gene Name

PTGS1

UniProt Synonym Gene Names

COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1

NCBI Protein Information

prostaglandin G/H synthase 1

NCBI Summary for PTGS1

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt Comments for PTGS1

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.

Research Articles on PTGS1

1. We provide the first report that pro-angiogenic genes PECAM1, PTGS1, FGD5, and MCAM may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PTGS1 elisa kit

Reference Product	PubMed Publications
PLA2G4A elisa kit	>101 publications with PTGS1 and PLA2G4A
PTGES2 elisa kit	>19 publications with PTGS1 and PTGES2
PTGIS elisa kit	>10 publications with PTGS1 and PTGIS
PTGES3 elisa kit	>6 publications with PTGS1 and PTGES3
TBXAS1 elisa kit	>4 publications with PTGS1 and TBXAS1
ALOX15B elisa kit	>2 publications with PTGS1 and ALOX15B
PLA2G5 elisa kit	>2 publications with PTGS1 and PLA2G5

Pathways associated with PTGS1 elisa kit

Products by Pathway	Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Arachidonic Acid Metabolism Pathway antibodies	Arachidonic Acid Metabolism Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
C20 Prostanoid Biosynthesis Pathway antibodies	C20 Prostanoid Biosynthesis Pathway Diagram
C20 Prostanoid Biosynthesis Pathway antibodies	C20 Prostanoid Biosynthesis Pathway Diagram
COX Reactions Pathway antibodies	COX Reactions Pathway Diagram
Eicosanoid Synthesis Pathway antibodies	Eicosanoid Synthesis Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram

Diseases associated with PTGS1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>1108 publications with PTGS1 and Inflammation
Cardiovascular Diseases Antibodies	>550 publications with PTGS1 and Cardiovascular Diseases
Pain Antibodies	>384 publications with PTGS1 and Pain
Necrosis Antibodies	>313 publications with PTGS1 and Necrosis
Carcinoma Antibodies	>283 publications with PTGS1 and Carcinoma
Edema Antibodies	>272 publications with PTGS1 and Edema
Heart Diseases Antibodies	>184 publications with PTGS1 and Heart Diseases
Hypertension Antibodies	>164 publications with PTGS1 and Hypertension
Stomach Ulcer Antibodies	>157 publications with PTGS1 and Stomach Ulcer
Kidney Diseases Antibodies	>112 publications with PTGS1 and Kidney Diseases

Organs/Tissues associated with PTGS1 elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1403 publications with PTGS1 and Blood
Vascular Antibodies	>761 publications with PTGS1 and Vascular
Brain Antibodies	>407 publications with PTGS1 and Brain
Stomach Antibodies	>380 publications with PTGS1 and Stomach
Muscle Antibodies	>379 publications with PTGS1 and Muscle
Kidney Antibodies	>317 publications with PTGS1 and Kidney
Heart Antibodies	>290 publications with PTGS1 and Heart
Intestine Antibodies	>234 publications with PTGS1 and Intestine
Lung Antibodies	>228 publications with PTGS1 and Lung
Liver Antibodies	>215 publications with PTGS1 and Liver