Defensin Beta 1 (DEFb1) ELISA Kit for Human

Name: Human DEFb1 ELISA Kit; Defensin Beta 1; MyBioSource
Brand: MyBioSource
SKU: MBS455436
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455436

MBS455436 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Defensin Beta 1 (DEFb1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Defensin Beta 1 (DEFb1), ELISA Kit

Full Product Name

Human Defensin Beta 1 (DEFb1) ELISA Kit

Product Gene Name

DEFb1 elisa kit

Product Synonym Names

B-DF1; DEFB1; BD1; DEF-B1; DEFB101; HBD1

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Detection Range

62.5-4000pg/mL

Sensitivity

25.3pg/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

7,420 Da

3D Structure

ModBase 3D Structure for P60022

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of DEFb1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DEFb1. It may not necessarily be applicable to this product.

NCBI GI #

4885181

NCBI GeneID

1672

NCBI Accession #

NP_005209.1

UniProt Primary Accession #

P60022

UniProt Secondary Accession #

Q09753

UniProt Related Accession #

P60022

GenBank Nucleotide #

NM_005218.3

NCBI Official Full Name

beta-defensin 1 preproprotein

NCBI Official Synonym Full Names

defensin beta 1

NCBI Official Symbol

DEFB1

NCBI Official Synonym Symbols

BD1; HBD1; DEFB-1; DEFB101

UniProt Protein Name

Beta-defensin 1

UniProt Synonym Protein Names

Defensin, beta 1

Protein Family

Beta-defensin

UniProt Gene Name

DEFB1

UniProt Synonym Gene Names

BD1; HBD1; BD-1; hBD-1

NCBI Protein Information

beta-defensin 1

NCBI Summary for DEFb1

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]

UniProt Comments for DEFb1

Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636).

Research Articles on DEFb1

1. The -44 CC genotype of the beta-defensin-1 gene (DEFB1 rs1800972) may be associated with susceptibility to chronic periodontitis in Japanese.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DEFb1 elisa kit

Reference Product	PubMed Publications
DEFB4A elisa kit	>143 publications with DEFb1 and DEFB4A
CAMP elisa kit	>11 publications with DEFb1 and CAMP
DEFA6 elisa kit	>5 publications with DEFb1 and DEFA6
DEFA5 elisa kit	>5 publications with DEFb1 and DEFA5
CCR6 elisa kit	>4 publications with DEFb1 and CCR6
DEFA4 elisa kit	>4 publications with DEFb1 and DEFA4
MYC elisa kit	>3 publications with DEFb1 and MYC
PAX2 elisa kit	>2 publications with DEFb1 and PAX2
DEFA3 elisa kit	>2 publications with DEFb1 and DEFA3

Pathways associated with DEFb1 elisa kit

Products by Pathway	Pathway Diagram
Antimicrobial Peptides Pathway antibodies	Antimicrobial Peptides Pathway Diagram
Beta Defensins Pathway antibodies	Beta Defensins Pathway Diagram
Defensins Pathway antibodies	Defensins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram

Diseases associated with DEFb1 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>70 publications with DEFb1 and Inflammation
Immune System Diseases Antibodies	>50 publications with DEFb1 and Immune System Diseases
Necrosis Antibodies	>38 publications with DEFb1 and Necrosis
Lung Diseases Antibodies	>35 publications with DEFb1 and Lung Diseases
Carcinoma Antibodies	>24 publications with DEFb1 and Carcinoma
Fibrosis Antibodies	>18 publications with DEFb1 and Fibrosis
Kidney Diseases Antibodies	>10 publications with DEFb1 and Kidney Diseases
Pneumonia Antibodies	>8 publications with DEFb1 and Pneumonia
Diabetes Mellitus Antibodies	>6 publications with DEFb1 and Diabetes Mellitus
Precancerous Conditions Antibodies	>5 publications with DEFb1 and Precancerous Conditions

Organs/Tissues associated with DEFb1 elisa kit

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>44 publications with DEFb1 and Skin
Kidney Antibodies	>32 publications with DEFb1 and Kidney
Intestine Antibodies	>24 publications with DEFb1 and Intestine
Prostate Antibodies	>7 publications with DEFb1 and Prostate
Muscle Antibodies	>6 publications with DEFb1 and Muscle
Brain Antibodies	>5 publications with DEFb1 and Brain
Thyroid Antibodies	>3 publications with DEFb1 and Thyroid
Pancreas Antibodies	>2 publications with DEFb1 and Pancreas
Connective Tissue Antibodies	>2 publications with DEFb1 and Connective Tissue