Melanoma Cell Adhesion Molecule (MCAM) ELISA Kit for Human

Name: Human MCAM ELISA Kit; Melanoma Cell Adhesion Molecule; MyBioSource
Brand: MyBioSource
SKU: MBS455701
Price: 495 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS455701

MBS455701 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Melanoma Cell Adhesion Molecule (MCAM) ELISA Kit target analytes in biological samples. The concentration gradients of… More details

$495 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Melanoma Cell Adhesion Molecule (MCAM), ELISA Kit

Full Product Name

Human Melanoma Cell Adhesion Molecule (MCAM) ELISA Kit

Product Gene Name

MCAM elisa kit

Product Synonym Names

CD146; MUC18; Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; S-endo 1 endothelial-associated antigen

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, plasma, tissue homogenates and other biological fluids.

Detection Range

3.125-200ng/mL

Sensitivity

1.21ng/mL

Preparation and Storage

For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Molecular Weight

57,605 Da

OMIM

M29277 mRNA

3D Structure

ModBase 3D Structure for P43121

Intra Assay

CV<10%

Inter Assay

CV<12%

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of MCAM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MCAM. It may not necessarily be applicable to this product.

NCBI GI #

71274107

NCBI GeneID

4162

NCBI Accession #

NP_006491.2

UniProt Primary Accession #

P43121

UniProt Secondary Accession #

O95812; Q59E86; Q6PHR3; Q6ZTR2

UniProt Related Accession #

P43121

GenBank Nucleotide #

NM_006500.2

NCBI Official Full Name

cell surface glycoprotein MUC18

NCBI Official Synonym Full Names

melanoma cell adhesion molecule

NCBI Official Symbol

MCAM

NCBI Official Synonym Symbols

CD146; MUC18

UniProt Protein Name

Cell surface glycoprotein MUC18

UniProt Synonym Protein Names

Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; CD_antigen: CD146

Protein Family

Cell surface glycoprotein

UniProt Gene Name

MCAM

UniProt Synonym Gene Names

MUC18

NCBI Protein Information

cell surface glycoprotein MUC18

UniProt Comments for MCAM

Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Research Articles on MCAM

1. We provide the first report that pro-angiogenic genes PECAM1, PTGS1, FGD5, and MCAM may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MCAM elisa kit

Reference Product	PubMed Publications
FGF2 elisa kit	>8 publications with MCAM and FGF2
PTK2 elisa kit	>4 publications with MCAM and PTK2
TGFB1 elisa kit	>4 publications with MCAM and TGFB1
ATF3 elisa kit	>2 publications with MCAM and ATF3
LGALS1 elisa kit	>2 publications with MCAM and LGALS1
ESR1 elisa kit	>2 publications with MCAM and ESR1
CYP1B1 elisa kit	>1 publications with MCAM and CYP1B1
EDN1 elisa kit	>1 publications with MCAM and EDN1

Diseases associated with MCAM elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>41 publications with MCAM and Inflammation
Disease Models, Animal Antibodies	>33 publications with MCAM and Disease Models, Animal
Lung Diseases Antibodies	>32 publications with MCAM and Lung Diseases
Adenocarcinoma Antibodies	>29 publications with MCAM and Adenocarcinoma
Neoplasms, Experimental Antibodies	>27 publications with MCAM and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>26 publications with MCAM and Cardiovascular Diseases
Lung Neoplasms Antibodies	>25 publications with MCAM and Lung Neoplasms
Breast Neoplasms Antibodies	>24 publications with MCAM and Breast Neoplasms
Nervous System Diseases Antibodies	>20 publications with MCAM and Nervous System Diseases
Liver Diseases Antibodies	>18 publications with MCAM and Liver Diseases

Organs/Tissues associated with MCAM elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>153 publications with MCAM and Blood
Vascular Antibodies	>119 publications with MCAM and Vascular
Bone Antibodies	>60 publications with MCAM and Bone
Skin Antibodies	>58 publications with MCAM and Skin
Lung Antibodies	>51 publications with MCAM and Lung
Embryonic Tissue Antibodies	>44 publications with MCAM and Embryonic Tissue
Bone Marrow Antibodies	>43 publications with MCAM and Bone Marrow
Muscle Antibodies	>33 publications with MCAM and Muscle
Liver Antibodies	>25 publications with MCAM and Liver
Brain Antibodies	>25 publications with MCAM and Brain