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Folate Receptor 2, Adult (FOLR2) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS456065

MBS456065 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Folate Receptor 2, Adult (FOLR2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Folate Receptor 2, Adult (FOLR2), ELISA Kit
Full Product Name
Human Folate Receptor 2, Adult (FOLR2) ELISA Kit
Product Gene Name
FOLR2 elisa kit
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.156-10ng/mL
Sensitivity
0.064ng/mL
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
Molecular Weight
29,280 Da
OMIM
X69516 Genomic DNA
3D Structure
ModBase 3D Structure for P14207
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of FOLR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FOLR2. It may not necessarily be applicable to this product.

NCBI GI #
166064050
NCBI GeneID
2350
NCBI Accession #
NP_000794.3
UniProt Primary Accession #
P14207
UniProt Secondary Accession #
Q05CA5; Q6GTE8
UniProt Related Accession #
P14207
GenBank Nucleotide #
NM_000803.4
NCBI Official Full Name
folate receptor beta
NCBI Official Synonym Full Names
folate receptor beta
NCBI Official Symbol
FOLR2
NCBI Official Synonym Symbols
FBP; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1
UniProt Protein Name
Folate receptor beta
UniProt Synonym Protein Names
Folate receptor 2; Folate receptor, fetal/placental; Placental folate-binding protein; FBP
Protein Family
Folate receptor
UniProt Gene Name
FOLR2
UniProt Synonym Gene Names
FR-beta; FBP
NCBI Protein Information
folate receptor beta

NCBI Summary for FOLR2

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for FOLR2

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
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Research Articles on FOLR2

1. we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1, FOLR2, CD68 and CD11b markers

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FOLR2 elisa kit

 Reference Product  PubMed Publications
 SLC19A1 elisa kit  >10 publications with FOLR2 and SLC19A1
 PCBP1 elisa kit  >1 publications with FOLR2 and PCBP1

Pathways associated with FOLR2 elisa kit

 Products by Pathway  Pathway Diagram
 Antifolate Resistance Pathway antibodies  Antifolate Resistance Pathway Diagram
 Antifolate Resistance Pathway antibodies  Antifolate Resistance Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Folate And Pterines Pathway antibodies  Metabolism Of Folate And Pterines Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram

Diseases associated with FOLR2 elisa kit

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >16 publications with FOLR2 and Inflammation
 Nervous System Diseases Antibodies  >8 publications with FOLR2 and Nervous System Diseases
 Neural Tube Defects Antibodies  >8 publications with FOLR2 and Neural Tube Defects
 Disease Models, Animal Antibodies  >6 publications with FOLR2 and Disease Models, Animal
 Ovarian Neoplasms Antibodies  >5 publications with FOLR2 and Ovarian Neoplasms
 Cardiovascular Diseases Antibodies  >4 publications with FOLR2 and Cardiovascular Diseases
 Adenocarcinoma Antibodies  >3 publications with FOLR2 and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >2 publications with FOLR2 and Cell Transformation, Neoplastic
 Liver Neoplasms Antibodies  >2 publications with FOLR2 and Liver Neoplasms
 Kidney Diseases Antibodies  >2 publications with FOLR2 and Kidney Diseases

Organs/Tissues associated with FOLR2 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >6 publications with FOLR2 and Lung
 Placenta Antibodies  >6 publications with FOLR2 and Placenta
 Kidney Antibodies  >5 publications with FOLR2 and Kidney
 Bone Antibodies  >2 publications with FOLR2 and Bone
 Spleen Antibodies  >2 publications with FOLR2 and Spleen
 Parathyroid Antibodies  >2 publications with FOLR2 and Parathyroid
 Muscle Antibodies  >2 publications with FOLR2 and Muscle
 Intestine Antibodies  >1 publications with FOLR2 and Intestine
 Connective Tissue Antibodies  >1 publications with FOLR2 and Connective Tissue
 Uterus Antibodies  >1 publications with FOLR2 and Uterus
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