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ERBB Receptor Feedback Inhibitor 1 (ERRFI1) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS457249

MBS457249 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the ERBB Receptor Feedback Inhibitor 1 (ERRFI1) ELISA Kit target analytes in biological samples. The concentration gradients… More details

$520 / 48 Tests +1 FREE 8GB USB

Product Documentation

PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ERBB Receptor Feedback Inhibitor 1 (ERRFI1), ELISA Kit
Full Product Name
Human ERBB Receptor Feedback Inhibitor 1 (ERRFI1) ELISA Kit
Product Gene Name
ERRFI1 elisa kit
Product Synonym Names
Mitogen-inducible gene 6 protein; receptor-associated late transducer; GENE-33; RALT
Species Reactivity
Human
Assay Type
Sandwich
Samples
Serum, Plasma, Tissue Homogenates or Other Biological Fluids
Detection Range
31.2-2000pg/mL
Sensitivity
12.5pg/mL
Molecular Weight
50,560 Da
OMIM
608069
3D Structure
ModBase 3D Structure for Q9UJM3
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of ERRFI1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ERRFI1. It may not necessarily be applicable to this product.

NCBI GI #
10047086
NCBI GeneID
54206
NCBI Accession #
NP_061821.1
UniProt Primary Accession #
Q9UJM3
UniProt Secondary Accession #
Q9NTG9; Q9UD05; B2RDX9
UniProt Related Accession #
Q9UJM3
GenBank Nucleotide #
NM_018948.3
NCBI Official Full Name
ERBB receptor feedback inhibitor 1
NCBI Official Synonym Full Names
ERBB receptor feedback inhibitor 1
NCBI Official Symbol
ERRFI1
NCBI Official Synonym Symbols
MIG6; RALT; MIG-6; GENE-33
UniProt Protein Name
ERBB receptor feedback inhibitor 1
UniProt Synonym Protein Names
Mitogen-inducible gene 6 protein; MIG-6
Protein Family
ERBB receptor feedback inhibitor
UniProt Gene Name
ERRFI1
UniProt Synonym Gene Names
MIG6; MIG-6
NCBI Protein Information
ERBB receptor feedback inhibitor 1

NCBI Summary for ERRFI1

ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995 [PubMed 7641805]). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000 [PubMed 10749885]; Fiorentino et al., 2000 [PubMed 11003669]).[supplied by OMIM, Mar 2008]
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UniProt Comments for ERRFI1

Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development ().
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Research Articles on ERRFI1

1. Cdc42 inhibition is required for Mig-6 suppression of cell migration induced by EGF

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ERRFI1 elisa kit

 Reference Product  PubMed Publications
 EGFR elisa kit  >31 publications with ERRFI1 and EGFR
 ERBB2 elisa kit  >4 publications with ERRFI1 and ERBB2
 SRC elisa kit  >3 publications with ERRFI1 and SRC
 ERBB4 elisa kit  >3 publications with ERRFI1 and ERBB4
 INS elisa kit  >1 publications with ERRFI1 and INS
 ERBB3 elisa kit  >1 publications with ERRFI1 and ERBB3

Pathways associated with ERRFI1 elisa kit

 Products by Pathway  Pathway Diagram
 EGF/EGFR Signaling Pathway antibodies  EGF/EGFR Signaling Pathway Diagram
 Signaling Pathways In Glioblastoma antibodies  Signaling Pathways In Glioblastoma Diagram

Diseases associated with ERRFI1 elisa kit

 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >8 publications with ERRFI1 and Hyperplasia
 Cardiovascular Diseases Antibodies  >4 publications with ERRFI1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >4 publications with ERRFI1 and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >4 publications with ERRFI1 and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >3 publications with ERRFI1 and Lung Neoplasms
 Hypertrophy Antibodies  >3 publications with ERRFI1 and Hypertrophy
 Skin Neoplasms Antibodies  >3 publications with ERRFI1 and Skin Neoplasms
 Fatty Liver Antibodies  >2 publications with ERRFI1 and Fatty Liver
 Inflammation Antibodies  >2 publications with ERRFI1 and Inflammation
 Heart Diseases Antibodies  >2 publications with ERRFI1 and Heart Diseases

Organs/Tissues associated with ERRFI1 elisa kit

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with ERRFI1 and Lung
 Uterus Antibodies  >7 publications with ERRFI1 and Uterus
 Blood Antibodies  >7 publications with ERRFI1 and Blood
 Liver Antibodies  >7 publications with ERRFI1 and Liver
 Brain Antibodies  >5 publications with ERRFI1 and Brain
 Skin Antibodies  >5 publications with ERRFI1 and Skin
 Pancreas Antibodies  >3 publications with ERRFI1 and Pancreas
 Heart Antibodies  >3 publications with ERRFI1 and Heart
 Bone Antibodies  >3 publications with ERRFI1 and Bone
 Thyroid Antibodies  >2 publications with ERRFI1 and Thyroid
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