Claudin 3 (CLDN3) ELISA Kit for Mouse

Name: Mouse CLDN3 ELISA Kit; Claudin 3; MyBioSource
Brand: MyBioSource
SKU: MBS458406
Price: 550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458406

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CLDN3. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to CLDN3.… More details

$550 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Claudin 3 (CLDN3), ELISA Kit

Full Product Name

Mouse Claudin 3 (CLDN3) ELISA Kit

Product Gene Name

CLDN3 elisa kit

Product Synonym Names

C7orf1; CPE-R2; CPETR2; HRVP1; RVP1; Clostridium Perfringens Enterotoxin Receptor 2; Ventral Prostate.1-Like Protein; CPE-Receptor 2

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

0.156-10ng/mL

Sensitivity

0.061ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

21,227 Da

3D Structure

ModBase 3D Structure for Q9Z0G9

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of CLDN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLDN3 purchase

MBS458406 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Claudin 3 (CLDN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CLDN3. The ELISA analytical biochemical technique of the MBS458406 kit is based on CLDN3 antibody-CLDN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLDN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLDN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CLDN3. It may not necessarily be applicable to this product.

NCBI GI #

6753438

NCBI GeneID

12739

NCBI Accession #

NP_034032.1

UniProt Primary Accession #

Q9Z0G9

UniProt Secondary Accession #

Q91X40

UniProt Related Accession #

Q9Z0G9

GenBank Nucleotide #

NM_009902.4

NCBI Official Full Name

claudin-3

NCBI Official Synonym Full Names

claudin 3

NCBI Official Symbol

Cldn3

NCBI Official Synonym Symbols

mRVP1; Cpetr2; AI182374

UniProt Protein Name

Claudin-3

UniProt Synonym Protein Names

Clostridium perfringens enterotoxin receptor 2; CPE-R 2; CPE-receptor 2

Protein Family

Claudin

UniProt Gene Name

Cldn3

UniProt Synonym Gene Names

Cpetr2; CPE-R 2; CPE-receptor 2

NCBI Protein Information

claudin-3

NCBI Summary for CLDN3

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens, and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane. This protein is highly overexpressed in uterine carcinosarcoma. This protein is also predominantly present in brain endothelial cells, where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology. [provided by RefSeq, Aug 2012]

UniProt Comments for CLDN3

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Research Articles on CLDN3

1. Claudin-3 was present in the fila olfactoria from the epithelium to the olfactory nerve and in the main and accessory olfactory bulb.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CLDN3 elisa kit

Reference Product	PubMed Publications
Cldn4 elisa kit	>130 publications with CLDN3 and Cldn4
Ocln elisa kit	>51 publications with CLDN3 and Ocln
Cldn7 elisa kit	>39 publications with CLDN3 and Cldn7
Tjp1 elisa kit	>33 publications with CLDN3 and Tjp1
Cldn10 elisa kit	>3 publications with CLDN3 and Cldn10
Cldn8 elisa kit	>3 publications with CLDN3 and Cldn8
Tjp2 elisa kit	>3 publications with CLDN3 and Tjp2
Cldn23 elisa kit	>2 publications with CLDN3 and Cldn23
Tjp3 elisa kit	>1 publications with CLDN3 and Tjp3

Pathways associated with CLDN3 elisa kit

Products by Pathway	Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Hepatitis C Pathway antibodies	Hepatitis C Pathway Diagram
Hepatitis C Pathway antibodies	Hepatitis C Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram
Leukocyte Transendothelial Migration Pathway antibodies	Leukocyte Transendothelial Migration Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
Tight Junction Pathway antibodies	Tight Junction Pathway Diagram
XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies	XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with CLDN3 elisa kit

Disease Name	Pubmed Publications
Carcinoma Antibodies	>74 publications with CLDN3 and Carcinoma
Adenocarcinoma Antibodies	>46 publications with CLDN3 and Adenocarcinoma
Ovarian Neoplasms Antibodies	>38 publications with CLDN3 and Ovarian Neoplasms
Breast Neoplasms Antibodies	>24 publications with CLDN3 and Breast Neoplasms
Inflammation Antibodies	>21 publications with CLDN3 and Inflammation
Necrosis Antibodies	>18 publications with CLDN3 and Necrosis
Nervous System Diseases Antibodies	>14 publications with CLDN3 and Nervous System Diseases
Neoplasm Metastasis Antibodies	>14 publications with CLDN3 and Neoplasm Metastasis
Stomach Neoplasms Antibodies	>13 publications with CLDN3 and Stomach Neoplasms
Lung Neoplasms Antibodies	>9 publications with CLDN3 and Lung Neoplasms

Organs/Tissues associated with CLDN3 elisa kit

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>49 publications with CLDN3 and Intestine
Lung Antibodies	>24 publications with CLDN3 and Lung
Liver Antibodies	>23 publications with CLDN3 and Liver
Kidney Antibodies	>18 publications with CLDN3 and Kidney
Stomach Antibodies	>17 publications with CLDN3 and Stomach
Testis Antibodies	>13 publications with CLDN3 and Testis
Prostate Antibodies	>12 publications with CLDN3 and Prostate
Embryonic Tissue Antibodies	>9 publications with CLDN3 and Embryonic Tissue
Eye Antibodies	>8 publications with CLDN3 and Eye
Salivary Gland Antibodies	>8 publications with CLDN3 and Salivary Gland