Collagen Type XV (COL15) ELISA Kit for Human

Name: Human COL15 ELISA Kit; Collagen Type XV; MyBioSource
Brand: MyBioSource
SKU: MBS458460
Price: 540 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458460

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to COL15. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to COL15.… More details

$540 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Collagen Type XV (COL15), ELISA Kit

Full Product Name

Human Collagen Type XV (COL15) ELISA Kit

Product Gene Name

COL15 elisa kit

Product Synonym Names

COL15A1; COL15-A1; Collagen Alpha-1(XV)chain; Restin; Endostatin-XV; Related to endostatin

Species Reactivity

Human

Assay Type

Sandwich

Samples

Serum, Plasma, Tissue Homogenates or Other Biological Fluids.

Detection Range

0.312-20ng/mL

Sensitivity

0.121ng/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

141,720 Da

OMIM

120325

3D Structure

ModBase 3D Structure for P39059

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of COL15 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COL15 purchase

MBS458460 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Collagen Type XV (COL15) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing COL15. The ELISA analytical biochemical technique of the MBS458460 kit is based on COL15 antibody-COL15 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect COL15 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, COL15. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for COL15. It may not necessarily be applicable to this product.

NCBI GI #

116008152

NCBI GeneID

1306

NCBI Accession #

NP_001846.3

UniProt Primary Accession #

P39059

UniProt Secondary Accession #

Q5T6J4; Q9UDC5; Q9Y4W4

UniProt Related Accession #

P39059

GenBank Nucleotide #

NM_001855.4

NCBI Official Full Name

collagen alpha-1(XV) chain

NCBI Official Synonym Full Names

collagen type XV alpha 1 chain

NCBI Official Symbol

COL15A1

UniProt Protein Name

Collagen alpha-1(XV) chain

UniProt Synonym Protein Names

RestinAlternative name(s):Endostatin-XV; Related to endostatin; Restin-I

Protein Family

Zinc finger protein CONSTANS

UniProt Gene Name

COL15A1

NCBI Protein Information

collagen alpha-1(XV) chain

NCBI Summary for COL15

This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration. [provided by RefSeq, May 2013]

UniProt Comments for COL15

Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.

Research Articles on COL15

1. COL15A1 mRNA was up-regulated in hepatocellular cancer (HCC) and collagen XV was expressed along the sinusoid-like endothelium of HCC but not in non-tumoral regions, which implies that collagen XV contributes to the capillarization of HCC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with COL15 elisa kit

Reference Product	PubMed Publications
COL18A1 elisa kit	>16 publications with COL15 and COL18A1
COL3A1 elisa kit	>3 publications with COL15 and COL3A1
COL14A1 elisa kit	>2 publications with COL15 and COL14A1
COL6A1 elisa kit	>2 publications with COL15 and COL6A1
COL4A2 elisa kit	>2 publications with COL15 and COL4A2
COL6A2 elisa kit	>1 publications with COL15 and COL6A2
COL12A1 elisa kit	>1 publications with COL15 and COL12A1
COL6A3 elisa kit	>1 publications with COL15 and COL6A3

Pathways associated with COL15 elisa kit

Products by Pathway	Pathway Diagram
Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies	Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
Collagen Biosynthesis And Modifying Enzymes Pathway antibodies	Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
Collagen Degradation Pathway antibodies	Collagen Degradation Pathway Diagram
Collagen Formation Pathway antibodies	Collagen Formation Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram

Diseases associated with COL15 elisa kit

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with COL15 and Nervous System Diseases
Adenocarcinoma Antibodies	>2 publications with COL15 and Adenocarcinoma
Hypertension Antibodies	>2 publications with COL15 and Hypertension
Fibrosis Antibodies	>2 publications with COL15 and Fibrosis
Heart Diseases Antibodies	>2 publications with COL15 and Heart Diseases
Necrosis Antibodies	>2 publications with COL15 and Necrosis
Lung Diseases Antibodies	>1 publications with COL15 and Lung Diseases
Carcinoma, Hepatocellular Antibodies	>1 publications with COL15 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>1 publications with COL15 and Liver Diseases
Disease Models, Animal Antibodies	>1 publications with COL15 and Disease Models, Animal

Organs/Tissues associated with COL15 elisa kit

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>16 publications with COL15 and Muscle
Eye Antibodies	>9 publications with COL15 and Eye
Bone Antibodies	>8 publications with COL15 and Bone
Embryonic Tissue Antibodies	>6 publications with COL15 and Embryonic Tissue
Kidney Antibodies	>5 publications with COL15 and Kidney
Heart Antibodies	>5 publications with COL15 and Heart
Lung Antibodies	>5 publications with COL15 and Lung
Brain Antibodies	>4 publications with COL15 and Brain
Connective Tissue Antibodies	>4 publications with COL15 and Connective Tissue
Skin Antibodies	>4 publications with COL15 and Skin