Chemokine C-X-C-Motif Receptor 4 (CXCR4) ELISA Kit for Mouse

Name: Mouse CXCR4 ELISA Kit; Chemokine C-X-C-Motif Receptor 4; MyBioSource
Brand: MyBioSource
SKU: MBS458713
Price: 510 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS458713

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to CXCR4. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to CXCR4.… More details

$510 / 48 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Chemokine C-X-C-Motif Receptor 4 (CXCR4), ELISA Kit

Full Product Name

Mouse Chemokine C-X-C-Motif Receptor 4 (CXCR4) ELISA Kit

Product Gene Name

CXCR4 elisa kit

Product Synonym Names

CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3

Species Reactivity

Mouse

Assay Type

Sandwich

Samples

Tissue Homogenates, Cell Lysates or Other Biological Fluids.

Detection Range

78.1-5000pg/mL

Sensitivity

27.2pg/mL

Preparation and Storage

For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Molecular Weight

40,240 Da

3D Structure

ModBase 3D Structure for P70658

RTU ELISA Kit's Advantage

The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.

ISO Certification

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Other Notes

Small volumes of CXCR4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCR4 purchase

MBS458713 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Chemokine C-X-C-Motif Receptor 4 (CXCR4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CXCR4. The ELISA analytical biochemical technique of the MBS458713 kit is based on CXCR4 antibody-CXCR4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CXCR4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CXCR4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for CXCR4. It may not necessarily be applicable to this product.

NCBI GI #

116268123

NCBI GeneID

12767

NCBI Accession #

NP_034041.2

UniProt Primary Accession #

P70658

UniProt Secondary Accession #

O09059; O09062; P70233; P70346; Q4KMW1

UniProt Related Accession #

P70658

GenBank Nucleotide #

NM_009911.3

NCBI Official Full Name

C-X-C chemokine receptor type 4 isoform 1

NCBI Official Synonym Full Names

chemokine (C-X-C motif) receptor 4

NCBI Official Symbol

Cxcr4

NCBI Official Synonym Symbols

CD184; LESTR; Sdf1r; CXC-R4; CXCR-4; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1

UniProt Protein Name

C-X-C chemokine receptor type 4

UniProt Synonym Protein Names

Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; Pre-B-cell-derived chemokine receptor; PB-CKR; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD_antigen: CD184

Protein Family

C-X-C chemokine receptor

UniProt Gene Name

Cxcr4

UniProt Synonym Gene Names

Cmkar4; Lestr; Sdf1r; CXC-R4; CXCR-4; LESTR; PB-CKR; SDF-1 receptor

NCBI Protein Information

C-X-C chemokine receptor type 4

UniProt Comments for CXCR4

Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Research Articles on CXCR4

1. the Sdf-1 receptors - Cxcr4 and Cxcr7, as well as signaling pathways induced by these molecules in primary myoblasts, as well as various stem cells, were studied.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CXCR4 elisa kit

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram

Diseases associated with CXCR4 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>661 publications with CXCR4 and Inflammation
Neoplasm Metastasis Antibodies	>625 publications with CXCR4 and Neoplasm Metastasis
Disease Models, Animal Antibodies	>486 publications with CXCR4 and Disease Models, Animal
Nervous System Diseases Antibodies	>449 publications with CXCR4 and Nervous System Diseases
Breast Neoplasms Antibodies	>399 publications with CXCR4 and Breast Neoplasms
Lung Diseases Antibodies	>321 publications with CXCR4 and Lung Diseases
Necrosis Antibodies	>295 publications with CXCR4 and Necrosis
Lung Neoplasms Antibodies	>238 publications with CXCR4 and Lung Neoplasms
Heart Diseases Antibodies	>222 publications with CXCR4 and Heart Diseases
Neoplasms, Experimental Antibodies	>217 publications with CXCR4 and Neoplasms, Experimental

Organs/Tissues associated with CXCR4 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Marrow Antibodies	>1432 publications with CXCR4 and Bone Marrow
Brain Antibodies	>679 publications with CXCR4 and Brain
Lymph Node Antibodies	>424 publications with CXCR4 and Lymph Node
Muscle Antibodies	>338 publications with CXCR4 and Muscle
Embryonic Tissue Antibodies	>273 publications with CXCR4 and Embryonic Tissue
Spleen Antibodies	>183 publications with CXCR4 and Spleen
Thymus Antibodies	>133 publications with CXCR4 and Thymus
Intestine Antibodies	>101 publications with CXCR4 and Intestine
Eye Antibodies	>72 publications with CXCR4 and Eye
Spinal Cord Antibodies	>55 publications with CXCR4 and Spinal Cord